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The Annals of Thoracic Surgery, Vol 42, 644-650, Copyright © 1986 by The Society of Thoracic Surgeons
RL Beaudet, NL Poirier, D Doyle, G Nakhle and C Gauvin
Clinical information on the Medtronic-Hall valve prosthesis was obtained by
reviewing the records of 379 patients, 164 of whom had aortic valve
replacement (AVR), 163 of whom had mitral valve replacement (MVR), and 52
of whom had double valve replacement over 90 months (1,225 patient-years)
(mean follow-up, 42.01 +/- 1.3 months [+/- standard error]). Mean age was
53.8 +/- 12 years. One hundred ninety- three patients (50.9%) had some type
of concomitant operation, such as tricuspid annuloplasty, coronary artery
bypass grafting, or resection of ascending aortic aneurysm. Ninety-one
percent were in New York Heart Association (NYHA) Functional Class III or
IV preoperatively. Early mortality and late mortality were 7.7% (29
patients) and 13.5% (51 patients), respectively. The actuarial survival at
7 1/2 years was 74.1 +/- 2.7% for the total group and 69.0 +/- 4.5% for
those having AVR, 81.0 +/- 3.2% for those having MVR, and 67.0 +/- 8.9% for
those having double valve replacement. All patients but 2 were maintained
on a regimen of chronic anticoagulation with warfarin sodium. Twenty-six
thromboembolic episodes occurred (2.1/100 patient-years): 13 after MVR
(2.3/100 patient-years), 11 after AVR (2.1/100 patient-years), and 2 after
double valve replacement (1.4/100 patient-years). Four thromboembolic
episodes were fatal; no valve thrombosis occurred. There were no structural
failures. Of the 350 late survivors, 92% were in NYHA Functional Classes I
and II. Total valve-related complications have been minimal.(ABSTRACT
TRUNCATED AT 250 WORDS)
ARTICLES
The Medtronic-Hall cardiac valve: 7 1/2 years' clinical experience
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