ATS
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
 QUICK SEARCH:   [advanced]


     


This Article
Right arrow Full Text (PDF)
Right arrow References
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Personal Folders
Right arrow Download to citation manager
Right arrow Permission Requests
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Dark, J. H.
Right arrow Articles by Cooper, J. D.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Dark, J. H.
Right arrow Articles by Cooper, J. D.

Ann Thorac Surg 1986;42:394-398
© 1986 The Society of Thoracic Surgeons


Articles

Experimental En Bloc Double-Lung Transplantation

J.H. Dark, M.D., G.A. Patterson, M.D.*, A.N. Al-Jilaihawi, M.D., H. Hsu, M.D., T. Egan, M.D., J.D. Cooper, M.D.

From the Division of Thoracic Surgery, Department of Surgery, University of Toronto, Toronto, Ont, Canada

* Address reprint requests to Dr. Patterson, Division of Thoracic Surgery, Toronto General Hospital, Eaton Bldg N 10-230, Toronto, Ont, Canada M5G 1L7

A technique of en bloc double-lung transplantation through a median sternotomy has been developed. Hypothermic circulatory arrest was used after surface cooling in 7 puppies (mean weight, 3.1 kg; range, 1.5 to 4.1 kg). A double lung block, consisting of the two lungs, distal trachea, the main pulmonary artery, and a large cuff of left atrium, was removed from weight-matched donors. After the arrest of the circulation by inflow occlusion, bilateral pneumonectomies were performed in the recipient. The donor double-lung block was then implanted with anastomoses at the distal trachea, the posterior left atrium, and the main pulmonary artery.

All animals were successfully rewarmed and had excellent hemodynamic function and gas exchange for periods of up to 24 hours.

If primate experiments with long-term survival confirm these initial results, this procedure may have a role in the treatment of patients with end-stage respiratory disease but acceptable cardiac function.




This article has been cited by other articles:


Home page
Ann. Thorac. Surg.Home page
G. A. Patterson, J. D. Cooper, B. Goldman, R. D. Weisel, F. G. Pearson, P. F. Waters, T. R. Todd, H. Scully, M. Goldberg, and R. J. Ginsberg
Technique of Successful Clinical Double-Lung Transplantation
Ann. Thorac. Surg., June 1, 1988; 45(6): 626 - 633.
[Abstract] [PDF]


Home page
Ann. Thorac. Surg.Home page
J. D. Cooper
Lung Transplantation: A New Era
Ann. Thorac. Surg., November 1, 1987; 44(5): 447 - 448.
[PDF]




HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
ANN THORAC SURG ASIAN CARDIOVASC THORAC ANN EUR J CARDIOTHORAC SURG
J THORAC CARDIOVASC SURG ICVTS ALL CTSNet JOURNALS
Copyright © 1986 by The Society of Thoracic Surgeons.