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Ann Thorac Surg 1986;42:97-99
© 1986 The Society of Thoracic Surgeons

Articles

Repair of Ventricular Septal Defect and Aortic Regurgitation Associated with Severe Hemophilia B

Alessandro Mazzucco, M.D.*, Giovanni Stellin, M.D., Paola Cantele, M.D., Mauro Boschello, M.D., Agostino Traldi, M.D., Vincenzo Gallucci, M.D.

From the Departments of Cardiovascular Surgery, Anesthesiology, and Cardiology, University of Padova Medical School, Padova, and the Department of Hematology, Hospital of Castelfranco Veneto, Treviso, Italy

Accepted for publication September 26, 1985.

* Address reprint requests to Dr. Mazzucco, Istituto di Chirurgia Cardiovascolare, Via Giustiniani 2, 35128 Padova, Italy

A child with severe factor IX deficiency who underwent an open-heart operation using extracorporeal circulation is described. The factor IX level was normalized immediately before operation and at the end of cardiopulmonary bypass by infusing prothrombin complex concentrate and fresh frozen plasma. Partial thromboplastin time and factor IX serum levels were monitored for 20 days postoperatively and showed factor IX activity higher than 50%.




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