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Ann Thorac Surg 1986;42:56-59
© 1986 The Society of Thoracic Surgeons

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Articles

Extracorporeal Membrane Oxygenation Experience at the University of Pittsburgh

From the Department of Surgery, University of Pittsburgh School of Mediane, Pittsburgh, PA

Accepted for publication October 21, 1985.

^* Address reprint requests to Dr. Trento, University of Pittsburgh School of Medicine, Department of Surgery, 1084 Scaife Hall, Pittsburgh, PA 15261

Between January, 1981, and May, 1985, 33 infants suffering from acute cardiorespiratory failure were treated with extracorporeal membrane oxygenation (ECMO) when all other forms of conventional management had failed. Only the patients with respiratory failure that was thought to be reversible were treated. Prolonged conventional respiratory management (more than five days) was considered a contraindication to ECMO support because of irreversible damage to the lungs caused by the barotrauma associated with conventional ventilation. Eighteen of the 33 patients (54%) survived and were discharged from the hospital. Patients with congenital diaphragmatic hernia had a high incidence of fatal bleeding complications (8 of 14). Good results were obtained in the newborns with persistent fetal circulation and meconium aspiration syndrome. We conclude that ECMO markedly improves the survival of newborns with severe respiratory failure who would have a mortality close to 100% with conventional respiratory management.

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