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Ann Thorac Surg 1986;41:135-142
© 1986 The Society of Thoracic Surgeons
Departments of Medicine and Surgery, Uniformed Services University of the Health Sciences, Bethesda, the Division of Gastroenterology, Naval Medical Center-National Capital Region, Bethesda, MD, the Cardiothoracic Surgery Service, Walter Reed Army Medical Center, Washington, DC, and the Division of Surgery, Walter Reed Army Institute of Research, Washington, DC
Accepted for publication March 16, 1985.
* Address reprint requests to Dr. Cohen, University Hospital, H4/364, 600 Highland Ave, Madison, WI 53792
Minimal data are available about the Angelchik antireflux prosthesis although it has been inserted in more than 14,000 patients. The present animal study was designed to evaluate the effectiveness and mechanism of action of this prosthesis. A reproducible model of esophageal reflux in primates was created using a double myotomy. Lower esophageal sphincter (LES) pressure and reflux score were improved significantly in animals by insertion of an Angelchik antireflux prosthesis, a modified antireflux prosthesis, or a Nissen fundoplication. Manometrically determined LES length was increased after insertion of an Angelchik antireflux prosthesis but not by a Nissen fundoplication or sham operation. Complications after insertion of the modified prosthesis included intraluminal erosion, fibrous stricture, and slippage of the device over the stomach.
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