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The Annals of Thoracic Surgery, Vol 40, 542-545, Copyright © 1985 by The Society of Thoracic Surgeons
MK Ferguson, AG Little and DB Skinner
Thirteen patients required pleural drainage for postoperative chylothorax
with an average duration of leakage of 36.9 days. Total protein and albumin
levels, body weight, and peripheral lymphocyte counts all decreased
substantially during the period of chylous leakage. Only 3 chylothoraces
resolved with tube drainage and dietary management alone. Six patients
required eight operations for control of chylothorax, and 4 patients, all
of whom had cancer, died with a persistent leak. chylothorax is a
debilitating postoperative complication resulting in an impaired immune
system and nutritional state. Because it is associated with a 50% mortality
in patients with cancer, early reoperation should be considered. Patients
with benign underlying disease can be managed conservatively for longer
periods. Control of potential chylous leaks at the time of original
operation is vital, especially in patients with malignancies who have a
predisposition toward leakage from sites other than the main thoracic duct.
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