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The Annals of Thoracic Surgery, Vol 40, 35-40, Copyright © 1985 by The Society of Thoracic Surgeons
DG Pennington, HM Dennis, MT Swartz, S Nouri, SC Chen, F Azzam and JF Schweiss
From 1962 to mid-1984, 63 infants underwent coarctation repair. Cardiac
defects were present in 46 (73%). Repair was by subclavian aortoplasty in
35 patients, resection and end-to-end anastomosis in 19, and other
techniques in 6. Three patients died before the repair was completed. In 15
patients, an intraluminal shunt was used during subclavian aortoplasty.
Prostaglandin E1 (PGE1) was infused in 9 patients. Early (thirty-day)
mortality was 16% (10 patients): 4 patients who underwent end-to-end
anastomosis; 3 during attempted end-to-end anastomosis; 2 who received
bypass grafts; and 1 who had subclavian aortoplasty without a shunt. None
of the 15 patients who had subclavian aortoplasty with a shunt died. There
were no early deaths among the last 25 patients seen. One patient who
underwent subclavian aortoplasty without a shunt is paraplegic. There were
10 late deaths among the 53 patients followed from 1 month to 12 years
(mean, 3 years). Arm-leg pressure gradients of 20 mm Hg or greater were
found in 4 of the patients who had end-to-end anastomosis but not in any of
the patients who had subclavian aortoplasty. Improved results of
coarctation repair in infants in this study were attributed to PGE1,
subclavian aortoplasty, and use of an intraluminal shunt.
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