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The Annals of Thoracic Surgery, Vol 39, 16-26, Copyright © 1985 by The Society of Thoracic Surgeons
DG Pennington, JP Merjavy, MT Swartz, JE Codd, HB Barner, D Lagunoff, H Bashiti, GC Kaiser and VL Willman
To evaluate the importance of severe biventricular failure in patients with
postcardiotomy ventricular failure, we analyzed the data from 30 patients
treated with ventricular assist devices (VADs) over a five- year period.
All patients had profound postoperative ventricular failure refractory to
drugs and an intraaortic balloon (IAB). Evaluation of preoperative
ventricular function did not allow prediction of which patients would
require VADs. However, the development of perioperative myocardial
infarction was an important determinant of the need for postoperative
support with a VAD. Twenty patients received only a left VAD (LVAD). Four
of them had isolated left ventricular failure; 3 were weaned, and 2
survived. None of the 16 patients with biventricular failure who received
only an LVAD were weaned. Ten other patients with biventricular failure
received biventricular support, either with a right VAD and IAB, or with
two VADs. Of these 10 patients, 5 were weaned and 3 survived. Considering
all 26 patients with biventricular failure, those receiving biventricular
mechanical support (10) had a better chance (p less than 0.025) of being
weaned (5/10) and surviving (3/10) than those who received only an LVAD
(0/16). We conclude that biventricular failure is common in patients with
postcardiotomy ventricular failure and is often the result of perioperative
infarction. While patients with isolated left ventricular failure did well
with an LVAD only, those with biventricular failure required biventricular
mechanical support for survival.
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