The Annals of Thoracic Surgery, Vol 38, 444-446, Copyright © 1984 by The Society of Thoracic Surgeons
Thoracotomy as a staging procedure after chemotherapy in the treatment of Stage III nonseminomatous carcinoma of the testis
K Prenger, L Eysman, JN van der Heide, J Oldhoff, DT Sleijfer, HS Koops and JW Oosterhuis
Of 108 patients with a nonseminomatous testicular carcinoma, 28 with lung
metastases were studied. After combination chemotherapy with cisplatin,
vinblastine, and bleomycin (PVB), 11 patients underwent exploratory
thoracotomy. Viable carcinomatous tissue, along with fibrosis, necrosis,
and mature teratoma, was found in 4 patients. Three of these patients were
successfully retreated with VP 16-213, cisplatin, and actinomycin D. In
patients with residual pulmonary or mediastinal masses after chemotherapy,
resection of the lesions is mandatory to demonstrate viable carcinoma so
that treatment can be readministered. Thus, in our view, thoracotomy is a
diagnostic procedure.