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The Annals of Thoracic Surgery, Vol 38, 406-408, Copyright © 1984 by The Society of Thoracic Surgeons

ARTICLES

Coronary artery bypass in hereditary factor XI deficiency

R Brunken, D Follette and J Wittig

Hereditary factor XI deficiency is a disorder of coagulation that has been associated with postoperative bleeding. Because cardiopulmonary bypass itself induces transient abnormalities in hemostasis, the patient with factor XI deficiency could be at increased risk for bleeding after cardiac surgical procedures. We report the successful management of a 61-year-old man with hereditary factor XI deficiency who had coronary artery bypass. Treatment with low-dose aspirin, begun 24 hours postoperatively for graft patency, was well tolerated. Once recognized and aggressively treated, factor XI deficiency does not appear to be a contraindication to potentially life-saving procedures like coronary revascularization.


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