HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Personal Folders Download to citation manager Permission Requests Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Mountain, C. F. Articles by Hermes, K. E. Search for Related Content PubMed PubMed Citation Articles by Mountain, C. F. Articles by Hermes, K. E.

The Annals of Thoracic Surgery, Vol 38, 323-330, Copyright © 1984 by The Society of Thoracic Surgeons

ARTICLES

Surgery for pulmonary metastasis: a 20-year experience

CF Mountain, MJ McMurtrey and KE Hermes

During a recent 20-year period, 556 patients underwent operation for pulmonary metastasis at the University of Texas M.D. Anderson Hospital and Tumor Institute at Houston. The surgical mortality was 1.5% for 772 resections. A selection of 443 patients was made to evaluate the contribution of operative intervention as a primary treatment, with selective adjunctive therapy when applicable. The success of a surgical approach is dependent primarily on adherence to selection criteria; it is important that only patients in whom all known disease can be completely removed with the planned resection and who have full control of the primary site are treated. The overall survival for the group was 35%. For patients with carcinoma, survival ranged from 24% for those with primary uterine cervix tumors to approximately 54% for urinary tract, male genital tract, and corpus of uterus primary tumors. In the group with sarcoma, patients with skeletal tumors had a 46.4% survival rate (50.7% for those with osteogenic sarcoma), and 33% of the patients with soft tissue tumors had long-term survival. The outcome for patients with melanoma was poor; only 12.1% survived 5 years. If the original criteria apply, multiple and bilateral lesions can be successfully managed. Patients undergoing planned adjuvant treatment had a superior outcome compared with those not so treated. However, a significant survival advantage was shown only for patients with sarcoma. The failure to control all disease in patients in whom pulmonary metastasis is controlled surgically can only be improved on through the use of systemically active adjuvant treatment.

This article has been cited by other articles:

				M. K. Gould, J. Fletcher, M. D. Iannettoni, W. R. Lynch, D. E. Midthun, D. P. Naidich, and D. E. Ost Evaluation of Patients With Pulmonary Nodules: When Is It Lung Cancer?: ACCP Evidence-Based Clinical Practice Guidelines (2nd Edition) Chest, September 1, 2007; 132(3_suppl): 108S - 130S. [Abstract] [Full Text] [PDF]

				S.-W. Kuo, Y.-L. Chang, P.-M. Huang, H.-H. Hsu, J.-S. Chen, J.-M. Lee, P.-H. Lee, and Y.-C. Lee Prognostic Factors for Pulmonary Metastasectomy in Hepatocellular Carcinoma Ann. Surg. Oncol., February 1, 2007; 14(2): 992 - 997. [Abstract] [Full Text] [PDF]

				O. Rena, E. Papalia, A. Oliaro, P. Filosso, E. Ruffini, G. Maggi, and C. Casadio Pulmonary metastases from epithelial tumours: late results of surgical treatment. Eur. J. Cardiothorac. Surg., August 1, 2006; 30(2): 217 - 222. [Abstract] [Full Text] [PDF]

				J. M. Clavero, C. Deschamps, S. D. Cassivi, M. S. Allen, F. C. Nichols III, B. A. Barrette, D. R. Larson, and P. C. Pairolero Gynecologic Cancers: Factors Affecting Survival After Pulmonary Metastasectomy Ann. Thorac. Surg., June 1, 2006; 81(6): 2004 - 2007. [Abstract] [Full Text] [PDF]

				A. Rolle, A. Pereszlenyi, R. Koch, M. Richard, and B. Baier Is surgery for multiple lung metastases reasonable? A total of 328 consecutive patients with multiple-laser metastasectomies with a new 1318-nm Nd:YAG laser J. Thorac. Cardiovasc. Surg., June 1, 2006; 131(6): 1236 - 1242. [Abstract] [Full Text] [PDF]

				M. Mae, T. P. O'Connor, and R. G. Crystal Gene Transfer of the Vascular Endothelial Growth Factor Receptor flt-1 Suppresses Pulmonary Metastasis Associated with Lung Growth Am. J. Respir. Cell Mol. Biol., December 1, 2005; 33(6): 629 - 635. [Abstract] [Full Text] [PDF]

				R. M. Suri, C. Deschamps, S. D. Cassivi, F. C. Nichols III, M. S. Allen, C. D. Schleck, and P. C. Pairolero Pulmonary Resection for Metastatic Malignant Fibrous Histiocytoma: An Analysis of Prognostic Factors Ann. Thorac. Surg., November 1, 2005; 80(5): 1847 - 1852. [Abstract] [Full Text] [PDF]

				A. M. Parsons, F. C. Detterbeck, and L. A. Parker Accuracy of Helical CT in the Detection of Pulmonary Metastases: Is Intraoperative Palpation Still Necessary? Ann. Thorac. Surg., December 1, 2004; 78(6): 1910 - 1918. [Abstract] [Full Text] [PDF]

				M. Inoue, M. Ohta, K. Iuchi, A. Matsumura, K. Ideguchi, T. Yasumitsu, K. Nakagawa, K. Fukuhara, H. Maeda, S.-i. Takeda, et al. Benefits of surgery for patients with pulmonary metastases from colorectal carcinoma Ann. Thorac. Surg., July 1, 2004; 78(1): 238 - 244. [Abstract] [Full Text] [PDF]

				K. Yamamoto, H. Yoshikawa, K. Shiromizu, T. Saito, K. Kuzuya, R. Tsunematsu, and T. Kamura Pulmonary metastasectomy for uterine cervical cancer: a multivariate analysis Ann. Thorac. Surg., April 1, 2004; 77(4): 1179 - 1182. [Abstract] [Full Text] [PDF]

				A. Monteiro, N. Arce, J. Bernardo, L. Eugenio, and M. J. Antunes Surgical resection of lung metastases from epithelial tumors Ann. Thorac. Surg., February 1, 2004; 77(2): 431 - 437. [Abstract] [Full Text] [PDF]

				F. Loehe, S. Kobinger, R. A. Hatz, T. Helmberger, U. Loehrs, and H. Fuerst Value of systematic mediastinal lymph node dissection during pulmonary metastasectomy Ann. Thorac. Surg., July 1, 2001; 72(1): 225 - 229. [Abstract] [Full Text] [PDF]

				M. T. Jaklitsch, C. M. Mery, J. M. Lukanich, W. G. Richards, R. Bueno, S. J. Swanson, S. J. Mentzer, B. D. Davis, E. N. Allred, and D. J. Sugarbaker Sequential thoracic metastasectomy prolongs survival by re-establishing local control within the chest J. Thorac. Cardiovasc. Surg., April 1, 2001; 121(4): 657 - 667. [Abstract] [Full Text] [PDF]

				H. N. Koong, U. Pastorino, and R. J. Ginsberg Is there a role for pneumonectomy in pulmonary metastases? Ann. Thorac. Surg., December 1, 1999; 68(6): 2039 - 2043. [Abstract] [Full Text] [PDF]

				J. B. Zwischenberger and S. K. Alpard Pulmonary metastasectomy Ann. Thorac. Surg., July 1, 1999; 68(1): 287 - 288. [Full Text] [PDF]

				M. Antunes, J. Bernardo, M. Salete, D. Prieto, L. Eugenio, and P. Tavares Excision of pulmonary metastases of osteogenic sarcoma of the limbs Eur. J. Cardiothorac. Surg., May 1, 1999; 15(5): 592 - 596. [Abstract] [Full Text] [PDF]

				J. H. Robert, V. Ambrogi, B. Mermillod, D. Dahabreh, and P. Goldstraw Factors Influencing Long-Term Survival After Lung Metastasectomy Ann. Thorac. Surg., March 1, 1997; 63(3): 777 - 784. [Abstract] [Full Text]

				The International Registry of Lung Metastases, Writing Committee:, U. Pastorino, M. Buyse, G. Friedel, R. J. Ginsberg, P. Girard, P. Goldstraw, M. Johnston, P. McCormack, et al. LONG-TERM RESULTS OF LUNG METASTASECTOMY: PROGNOSTIC ANALYSES BASED ON 5206 CASES J. Thorac. Cardiovasc. Surg., January 1, 1997; 113(1): 37 - 49. [Abstract] [Full Text]

				C. P. Murrah, E. R. Ferguson, R. L. Jennelle, B. L. Guthrie, and W. L. Holman Resection of Multiple Pulmonary Metastases From a Recurrent Intracranial Meningioma Ann. Thorac. Surg., June 1, 1996; 61(6): 1823 - 1824. [Abstract] [Full Text]

				L. Tafra, P. S. Dale, L. A. Wanek, K. P. Ramming, and D. L. Morton Resection and adjuvant immunotherapy for melanoma metastatic to the lung and thorax J. Thorac. Cardiovasc. Surg., July 1, 1995; 110(1): 119 - 129. [Abstract] [Full Text]