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Ann Thorac Surg 1984;38:207-210
© 1984 The Society of Thoracic Surgeons
* Visiting clinician from the Division of Thoracic Surgery, Veterans General Hospital, Taipei, Taiwan, Republic of China
Sections of Thoracic, Cardiovascular, Vascular, and General Surgery and Surgical Pathology, Mayo Clinic and Mayo Foundation, Rochester, MN
Accepted for publication February 6, 1984.
* Address reprint requests to Dr. Payne, Mayo Clinic, 200 First St SW, Rochester, MN 55905
The incidence of cancer in a pharyngoesophageal (Zenker's) diverticulum was 0.4% among 1,249 patients treated for such diverticula at the Mayo Clinic in a 53-year period. Twenty-four patients with squamous cell carcinoma arising in a pharyngoesophageal diverticulum have been reported by others. However, most of the patients died of the malignancy within 2 years of treatment, and there were no long-term survivors. We describe 2 long-term survivors who were without evidence of tumor or diverticulum recurrence 4
and 8 years after one-stage pharyngoesophageal diverticulectomy. Review of the literature revealed that most patients with cancer in pharyngoesophageal diverticulum should be managed in a manner similar to that for patients with ordinary cervical esophageal malignancy. However, our data suggest that when the tumor is well localized without full-thickness penetration, nodal metastasis, or extension to the line of resection (as in the 2 patients discussed), diverticulectomy alone can provide satisfactory control of cancer with minimal therapeutic risk.
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