| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
The Annals of Thoracic Surgery, Vol 38, 124-127, Copyright © 1984 by The Society of Thoracic Surgeons
SR Gundry and MM Kirsh
Cardioplegic protection is limited by nonhomogeneous distribution of
solutions distal to coronary artery obstructions. Using temperature mapping
and sonomicrometry crystals implanted in the distributions of the left
anterior descending (LAD) and circumflex coronary arteries, we studied the
effects of blood cardioplegia delivery through the aortic root versus the
coronary sinus in 10 dogs with a temporarily occluded LAD. All dogs were
placed on cardiopulmonary bypass and cooled to 28 degrees C; the aorta was
cross-clamped for two hours with the LAD occluded. Group 1 (N = 5) had cold
(4 degrees C) potassium chloride cardioplegia (20 mEq per liter of KCl)
administered through the aortic root at 20-minute intervals; Group 2 (N =
5) had the same solution infused through the coronary sinus by a balloon
catheter. After two hours, the LAD snare was released and the dogs were
weaned from bypass. Aortic root cardioplegia resulted in very poor cooling
distal to the coronary obstruction with very poor systolic function and
loss of diastolic compliance. In contrast, coronary sinus cardioplegia
resulted in normal cooling distal to the coronary obstruction and complete
return of systolic and diastolic functions following the experimental
procedure. We conclude that cardioplegia administered through the coronary
sinus offers superior cooling distal to coronary artery obstructions while
preserving myocardial function in all areas. In contrast, delivery of
cardioplegia through the aortic root causes severe depression in the
myocardium distal to obstructions.
ARTICLES
A comparison of retrograde cardioplegia versus antegrade cardioplegia in the presence of coronary artery obstruction
This article has been cited by other articles:
|
|
 |
|
  J. P. Singh, S. Houser, E. K. Heist, and J. N. Ruskin The Coronary Venous Anatomy: A Segmental Approach to Aid Cardiac Resynchronization Therapy J. Am. Coll. Cardiol., July 5, 2005; 46(1): 68 - 74. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 G. Cohen, M. A. Borger, R. D. Weisel, and V. Rao Intraoperative myocardial protection: current trends and future perspectives Ann. Thorac. Surg., November 1, 1999; 68(5): 1995 - 2001. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 K. J Taft, A. H Stammers, C. C Jones, M. S Dickes, M. L Pierce, and D. J Beck Cardioplegia flow dynamics in an in vitro model Perfusion, September 1, 1999; 14(5): 341 - 349. [Abstract] [PDF]
|
|
|
|
 |
|
 T. A Abdel Aziz, N. Al Khaja, M. A Ali, A. S Maklad, M. F Bassiouny, M. Turner, and D. G Roberts Antegrade-Retrograde Cardioplegia for Myocardial Protection During Coronary Artery Bypass Graft Surgery Asian Cardiovasc Thorac Ann, September 1, 1998; 6(3): 188 - 194. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. V. Arom, R. W. Emery, R. J. Petersen, and J. W. Bero Evaluation of 7,000+ Patients With Two Different Routes of Cardioplegia Ann. Thorac. Surg., June 1, 1997; 63(6): 1619 - 1624. [Abstract] [Full Text]
|
|
|
|
 |
|
 S. Aronson Myocardial Contrast Echocardiography: Is it Ready to be Used as a Clinical Tool in the Operating Room? Seminars in Cardiothoracic and Vascular Anesthesia, March 1, 1997; 1(1): 4 - 15. [PDF]
|
|
|
|
|
|
G.-W. He Rare Complication of Retrograde Cardioplegia: Inner Wall Perforation of the Right Atrium Ann. Thorac. Surg., February 1, 1997; 63(2): 539 - 541. [Abstract] [Full Text]
|
|
|
|
|
|
S. R. Gundry, N. Wang, C. M. Sciolaro, G. S. Van Arsdell, A. J. Razzouk, A. C. Hill, and L. L. Bailey Uniformity of Perfusion in All Regions of the Human Heart by Warm Continuous Retrograde Cardioplegia Ann. Thorac. Surg., January 1, 1996; 61(1): 33 - 35. [Abstract] [Full Text]
|
|
|
|
|
|
R. N. Gates, H. Laks, D. C. Drinkwater Jr, A. Ardehali, A. S. Aharon, A. M. Zaragoza, and P. A. Chang Can Improved Microvascular Perfusion Be Achieved by Using Both Antegrade and Retrograde Cardioplegia? Ann. Thorac. Surg., November 1, 1995; 60(5): 1308 - 1311. [Abstract] [Full Text]
|
|
|
|
 |
|
 M. Galinanes, V. Argano, and D. J. Hearse Can Ischemic Preconditioning Ensure Optimal Myocardial Protection When Delivery of Cardioplegia Is Impaired? Circulation, November 1, 1995; 92(9): 389 - 394. [Abstract] [Full Text]
|
|
|
|
|
|
R. B. Moisa, S. M. Zeldis, S. A. Alper, and W. C. Scott Aortic Regurgitation in Coronary Artery Bypass Grafting: Implications for Cardioplegia Administration Ann. Thorac. Surg., September 1, 1995; 60(3): 665 - 668. [Abstract] [Full Text]
|
|
|
|
 |
|
 C. Quintilio, P. Voci, F. Bilotta, G. Luzi, F. Chiarotti, M. C. Acconcia, C. Mercanti, and B. Marino Risk factors of incomplete distribution of cardioplegic solution during coronary artery grafting J. Thorac. Cardiovasc. Surg., March 1, 1995; 109(3): 439 - 447. [Abstract] [Full Text]
|
|
|
|
|
|
O. Jegaden, A. Eker, P. Montagna, J. Ossette, C. Vial, J. Guidollet, and P. H. Mikaeloff Antegrade/Retrograde Cardioplegia in Arterial Bypass Grafting: Metabolic Randomized Clinical Trial Ann. Thorac. Surg., February 1, 1995; 59(2): 456 - 461. [Abstract] [Full Text]
|
|
|
|
|
|
J. Eng and C. Munsch Retrograde cardioplegia Perfusion, January 1, 1992; 7(1): 7 - 12. [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
| ANN THORAC SURG | ASIAN CARDIOVASC THORAC ANN | EUR J CARDIOTHORAC SURG |
| J THORAC CARDIOVASC SURG | ICVTS | ALL CTSNet JOURNALS |
