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Ann Thorac Surg 1983;36:270-280
© 1983 The Society of Thoracic Surgeons
From the Departments of Cardiovascular Surgery, The Ingham Medical Center, Lansing, MI, and the Palo Alto Medical Clinic, Health Care Division of the Palo Alto Medical Foundation, Palo Alto, CA
* Address reprint requests to Dr. Gonzalez-Lavin, Palo Alto Medical Clinic, 300 Homer Ave, Palo Alto, CA 94301
Between February, 1977, and April, 1982, 168 patients underwent aortic valve replacement (AVR) with an Ionescu-Shiley bovine pericardial valve. Concomitant procedures were performed in 71 patients. There were 12 hospital deaths (7.1%). Among patients having AVR only, there were 5 deaths (5.2%). Assessment included valve durability, incidence of thromboembolism, clinical improvement, and patient survival. There was 100% follow-up.
Actuarial freedom from intrinsic valve failure at 5 years was 96.3 ± 3.6%. Intrinsic valve failure occurred only once, 0.3 episodes per 100 patient-years. Four patients had thromboembolic complications. As for clinical status, 99.3% of surviving patients are in New York Heart Association Functional Class I or II, including 79 patients with valve sizes 17,19, or 21 mm (56%). Among 13 late deaths, 9 were related to the cardiovascular system. Overall patient survival is 84.9 ± 4.7%. Among the 92 patients with isolated AVR, 87.8 ± 5.9% are alive at the 5-year follow-up. If the incidence of valve failure is not altered in years to come, the durability of the Ionescu-Shiley bovine pericardial valve will surpass that of previous bioprostheses.
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