HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) References Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Personal Folders Download to citation manager Author home page(s): Edward V. Bennett, Jr. Frederick L. Grover Permission Requests Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Bennett, E. V. Articles by Trinkle, J. K. Search for Related Content PubMed PubMed Citation Articles by Bennett, E. V., Jr. Articles by Trinkle, J. K.

Ann Thorac Surg 1983;36:132-142
© 1983 The Society of Thoracic Surgeons

---

Articles

Myocardial Preservation: Effect of Venous Drainage

Division of Cardiothoracic Surgery of the University of Texas Health Science Center at San Antonio and the Audie Murphy Veterans Administration Hospital, San Antonio, TX

Accepted for publication October 4, 1982.

^* Address reprint requests to Dr. Bennett, Division of Cardiothoracic Surgery, UTHSCSA, 7703 Floyd Curl Dr, San Antonio, TX 78284

We compared the effect of three methods of venous drainage on myocardial temperature, coronary blood flow as determined with radioactive microspheres, myocardial metabolites (lactate, adenosine triphosphate [ATP], and glycogen), and left ventricular function before, during, and after cardiopulmonary bypass with hypothermic, hyperkalemic cardioplegic arrest. Venous drainage was established in the 6 dogs in Group 1 using a Sarns 51F cavoatrial catheter, in the 7 dogs in Group 2 using two USCI 32F vena caval catheters with tourniquets, and in the 7 dogs in Group 3 using two USCI 32F vena caval catheters without tourniquets. The lowest myocardial temperature was achieved in Group 1 (7.26° ± 0.45°C compared with 10.45° ± 0.56°C in Group 2 and 9.78° ± 0.43°C in Group 3) (p < 0.001). Myocardial rewarming to 20°C was not significantly different among the groups. Myocardial ATP and lactate levels were similar in all three groups. Myocardial glycogen levels were maintained during ischemia in Group 1 (1,010 ± 76 mg/dl compared with 686 ± 39 mg/dl in Group 2) (p < 0.005). Myocardial blood flow was similar in all groups during the preischemic periods, but during reperfusion a markedly decreased flow was seen in all areas of the myocardium in Group 1 compared with Group 2 (p < 0.004). Left ventricular function, as measured by the maximum rate of rise of left ventricular pressure, stroke work, and pressure/volume curves, was similar in all groups. We interpret the postischemic blood flow data, glycogen levels, and ventricular compliance differences to suggest that the dogs in Group 1 had less ischemia.

This article has been cited by other articles:

				W. Riley, D. FitzGerald, and L. Cohn Single, percutaneous, femoral venous cannulation for cardiopulmonary bypass Perfusion, May 1, 2007; 22(3): 211 - 215. [Abstract] [PDF]

				J. B Riley, S. B Hardin, B. A Winn, and M. B Hurdle In vitro comparison of cavoatrial (dual stage) cannulae for use during cardiopulmonary bypass Perfusion, July 1, 1986; 1(3): 197 - 204. [Abstract] [PDF]