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Ann Thorac Surg 1982;34:612-624
© 1982 The Society of Thoracic Surgeons

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Articles

Clinical and Hemodynamic Results with the Carpentier-Edwards Porcine Bioprosthesis

From the Departments of Surgery and Medicine, Montreal Heart Institute and Université de Montréal Medical School, Montreal, Que, Canada

^* Address reprint requests to Dr. Pelletier, Department of Surgery, Montreal Heart Institute, 5000 E Belanger St, Montreal, Que, Canada H1T 1C8

Carpentier-Edwards bioprostheses were implanted in 605 patients, 509 of whom had a single valve replacement, and 96 of whom had a multiple valve replacement. There were 54 early deaths (8.9%) and 26 late deaths (4.3%). The five-year actuarial survival was 87% for aortic valve replacement, 83% for mitral valve replacement, and 81% for multiple valve replacement. Of the 525 survivors, all but 3 were followed for a total of 964 patient-years; 354 patients (68%) remained asymptomatic, and 95 patients (18%) were improved. The incidences of thromboembolism, endocarditis, and reoperation due to primary tissue failure of the bioprosthesis were 2.0, 1.3, and 0.1% per patient-year, respectively. The actuarial probability of being free of all valve-related complications was 93% after five years. Satisfactory hemodynamic performance of the bioprosthesis was demonstrated by postoperative studies done in 70 patients. Thus, the Carpentier-Edwards porcine valve provides good clinical improvement, with a low incidence of valve-related complications and tissue failure at five years postoperatively.

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