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Ann Thorac Surg 1982;34:457-460
© 1982 The Society of Thoracic Surgeons


Articles

Intraoperative Use of Nifedipine for Hemodynamic Collapse Due to Coronary Artery Spasm Following Myocardial Revascularization

Gary S. Kopf, M.D.*, Arthur Riba, M.D., Rubin Zito, M.D.

Department of Surgery, Yale University School of Medicine, New Haven, and the West Haven Veterans Administration Medical Center, West Haven, CT

Accepted for publication September 18, 1981.

* Address reprint requests to Dr. Kopf, Yale University School of Medicine, Department of Surgery, 333 Cedar St., New Haven, CT 06510

Sudden hemodynamic collapse in the perioperative period following myocardial revascularization may be due to coronary artery spasm. Nitroglycerin has been the standard treatment for this; however, it is not always effective, and the resultant morbidity and mortality are high. We present the case of a patient in whom sudden hemodynamic collapse due to coronary artery spasm was refractory to intravenously administered nitroglycerin but was relieved quickly with sublingually administered nifedipine. In certain selected patients in whom coronary artery spasm is responsible for myocardial collapse, the drug nifedipine may be effective in relieving this spasm and allowing for myocardial recovery.




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