HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) References Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Personal Folders Download to citation manager Permission Requests Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Ghoneim, A. T. M. Articles by Ionescu, M. I. Search for Related Content PubMed PubMed Citation Articles by Ghoneim, A. T. M. Articles by Ionescu, M. I.

Ann Thorac Surg 1982;34:166-175
© 1982 The Society of Thoracic Surgeons

---

Articles

Serial C-reactive Protein Measurements in Infective Complications Following Cardiac Operation: Evaluation and Use in Monitoring Response to Therapy

From the Department of Microbiology, The University of Leeds, and the Cardiothoracic Unit, The General Infirmary at Leeds, Leeds, England

Accepted for publication October 8, 1981.

^* Address reprint requests to Mr. Ionescu, Department of Cardiothoracic Surgery, Leeds General Infirmary, Leeds LS1 3EX, England

Serum C-reactive protein (CRP) was studied serially in 100 patients who underwent cardiac operation and in another 17 patients in whom serious infections including prosthetic valve endocarditis developed in the early postoperative period. Eleven patients with late onset of prosthetic valve endocarditis and infective endocarditis were also investigated. The assay method used was radial immunodiffusion. Patients without postoperative infective complications showed a rapid increase in CRP levels, which reached a peak within 72 hours after operation followed by a progressive decline. The differences between the CRP levels in infected and uninfected patients were significant (p < 0.01). Serial measurements were of prognostic value in evaluating the response to chemotherapy and in predicting the outcome of the disease.

This article has been cited by other articles:

				M. Piccoli, E. Cerquetani, G. Pastena, A. Posteraro, E. Amici, M. D. Romeo, S. La Carrubba, and A. Salustri 'Lone' increase in C-reactive protein after cardiac surgery: prevalence, clinical characteristics, in-hospital course, and prognostic value European Journal of Cardiovascular Prevention & Rehabilitation, August 1, 2008; 15(4): 482 - 487. [Abstract] [Full Text] [PDF]

				D. W. M. Verhagen, A. C. Vedder, P. Speelman, and J. T. M. van der Meer Antimicrobial treatment of infective endocarditis caused by viridans streptococci highly susceptible to penicillin: historic overview and future considerations J. Antimicrob. Chemother., May 1, 2006; 57(5): 819 - 824. [Abstract] [Full Text] [PDF]

				R. Gambino C-Reactive Protein—Undervalued, Underutilized Clin. Chem., November 1, 1997; 43(11): 2017 - 2018. [Full Text] [PDF]

				I. Mitchell, L. Brady, J. Black, M. Jamieson, J. Pollock, and R. Logan The acute phase response to cardiopulmonary bypass in children Perfusion, March 1, 1996; 11(2): 103 - 112. [Abstract] [PDF]

				P. Icard, J.-P. Fleury, J.-F. Regnard, J.-M. Libert, P. Magdeleinat, N. Gharbi, A. Drachet, J.-F. Levi, and P. Levasseur Utility of C-reactive protein measurements for empyema diagnosis after pneumonectomy Ann. Thorac. Surg., April 1, 1994; 57(4): 933 - 936. [Abstract] [PDF]

				M. Leijala, K. Peltola, M. Aronen, S. Meri, and I. Louhimo Comparison of hollow fibre membrane oxygenators during cardiopulmonary bypass in children: Dideco Masterflo versus Terumo Capiox II Perfusion, January 1, 1990; 5(1): 33 - 43. [Abstract] [PDF]

				J. Miholic, M. Hudec, M. M. Muller, E. Domanig, and E. Wolner Early Prediction of Deep Sternal Wound Infection after Heart Operations by Alpha-1 Acid Glycoprotein and C-reactive Protein Measurements Ann. Thorac. Surg., October 1, 1986; 42(4): 429 - 433. [Abstract] [PDF]

				J. K. Kirklin, D. E. Chenoweth, D. C. Naftel, E. H. Blackstone, J. W. Kirklin, D. D. Bitran, J. G. Curd, J. G. Reves, and P. N. Samuelson Effects of Protamine Administration after Cardiopulmonary Bypass on Complement, Blood Elements, and the Hemodynamic State Ann. Thorac. Surg., February 1, 1986; 41(2): 193 - 199. [Abstract] [PDF]