|
|
||||||||
The Annals of Thoracic Surgery, Vol 33, 459-463, Copyright © 1982 by The Society of Thoracic Surgeons
MM Kirsh and H Sloan
A 17-year experience with 136 patients with bronchogenic carcinoma and
mediastinal metastases is reported. Six died postoperatively. Postoperative
mediastinal irradiation was given to 110 patients surviving curative
resection who had evidence of tumor spreading to the mediastinal lymph
nodes. The remaining 20 patients did not receive radiation therapy. Of the
136 patients, 29 (21.3%) lived 5 years free from disease and 9 survived 10
or more years. Of the 110 patients who survived operation and underwent
irradiation, 29 (26.4%) survived 5 years. None of the 20 patients not
receiving radiation therapy lived 5 years. Of the patients who underwent
irradiation, 18 of the 50 patients with squamous cell carcinoma survived 5
years, while only 7 of 55 with adenocarcinoma survived 5 years. We do not
believe that the discovery of mediastinal lymph node involvement in
bronchogenic carcinoma is a contraindication to pulmonary resection. As in
our previous reports, histological cell type has proved to be an important
indicator of absolute survival. Patients with squamous cell carcinoma had
an absolute-5-year survival of 33.9%, while the patients with
adenocarcinoma had an absolute survival of 12.3%. The level of lymph node
metastasis has an influence on prognosis as well. Patients with subcarinal
lymph node metastases had a lower survival than patients with superior
mediastinal involvement.
ARTICLES
Mediastinal metastases in bronchogenic carcinoma: influence of postoperative irradiation, cell type, and location
This article has been cited by other articles:
![]() |
L. A. Robinson, J. C. Ruckdeschel, H. Wagner Jr, and C. W. Stevens Treatment of Non-small Cell Lung Cancer-Stage IIIA: ACCP Evidence-Based Clinical Practice Guidelines (2nd Edition) Chest, September 1, 2007; 132(3_suppl): 243S - 265S. [Abstract] [Full Text] [PDF] |
||||
![]() |
T-E Strand, H Rostad, B Moller, and J Norstein Survival after resection for primary lung cancer: a population based study of 3211 resected patients Thorax, August 1, 2006; 61(8): 710 - 715. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. Riquet, C. Foucault, P. Berna, J. Assouad, A. Dujon, and C. Danel Prognostic Value of Histology in Resected Lung Cancer With Emphasis on the Relevance of the Adenocarcinoma Subtyping Ann. Thorac. Surg., June 1, 2006; 81(6): 1988 - 1995. [Abstract] [Full Text] [PDF] |
||||
![]() |
O. A. Khan, J. J. Fitzgerald, M. L. Field, I. Soomro, F. D. Beggs, W. E. Morgan, and J. P. Duffy Histological determinants of survival in completely resected T1-2N1M0 nonsmall cell cancer of the lung Ann. Thorac. Surg., April 1, 2004; 77(4): 1173 - 1178. [Abstract] [Full Text] [PDF] |
||||
![]() |
S. G. Spiro and J. C. Porter Lung Cancer--Where Are We Today?: Current Advances in Staging and Nonsurgical Treatment Am. J. Respir. Crit. Care Med., November 1, 2002; 166(9): 1166 - 1196. [Abstract] [Full Text] [PDF] |
||||
![]() |
J.F. Vansteenkiste and S.G. Stroobants The role of positron emission tomography with 18F-fluoro-2-deoxy-D-glucose in respiratory oncology Eur. Respir. J., April 1, 2001; 17(4): 802 - 820. [Abstract] [Full Text] [PDF] |
||||
![]() |
F. Andre, D. Grunenwald, J.-P. Pignon, A. Dujon, J. L. Pujol, P. Y. Brichon, L. Brouchet, E. Quoix, V. Westeel, and T. Le Chevalier Survival of Patients With Resected N2 Non-Small-Cell Lung Cancer: Evidence for a Subclassification and Implications J. Clin. Oncol., August 16, 2000; 18(16): 2981 - 2989. [Abstract] [Full Text] [PDF] |
||||
![]() |
J. H. Lee, M. Machtay, L. R. Kaiser, J. S. Friedberg, S. M. Hahn, M. G. McKenna, and W. G. McKenna Non-Small Cell Lung Cancer: Prognostic Factors in Patients Treated with Surgery and Postoperative Radiation Therapy Radiology, December 1, 1999; 213(3): 845 - 852. [Abstract] [Full Text] |
||||
![]() |
T. Naruke, R. Tsuchiya, H. Kondo, H. Nakayama, and H. Asamura Lymph node sampling in lung cancer: how should it be done? Eur. J. Cardiothorac. Surg., September 1, 1999; 16(suppl_1): S17 - S24. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. Okada, N. Tsubota, M. Yoshimura, Y. Miyamoto, and H. Matsuoka PROGNOSIS OF COMPLETELY RESECTED pN2 NON-SMALL CELL LUNG CARCINOMAS: WHAT IS THE SIGNIFICANT NODE THAT AFFECTS SURVIVAL? J. Thorac. Cardiovasc. Surg., August 1, 1999; 118(2): 270 - 275. [Abstract] [Full Text] [PDF] |
||||
![]() |
T. E. Sawyer, J. A. Bonner, P. M. Gould, R. L. Foote, C. Deschamps, V. F. Trastek, P. C. Pairolero, M. S. Allen, C. M. Lange, and H. Li Effectiveness of Postoperative Irradiation in Stage IIIA Non-Small Cell Lung Cancer According to Regression Tree Analyses of Recurrence Risks Ann. Thorac. Surg., November 1, 1997; 64(5): 1402 - 1407. [Abstract] [Full Text] |
||||
![]() |
J. F. Vansteenkiste, P. R. De Leyn, G. J. Deneffe, G. Stalpaert, K. L. Nackaerts, T. E. Lerut, and M. G. Demedts Survival and Prognostic Factors in Resected N2 Non-Small Cell Lung Cancer: A Study of 140 Cases Ann. Thorac. Surg., May 1, 1997; 63(5): 1441 - 1450. [Abstract] [Full Text] |
||||
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
| ANN THORAC SURG | ASIAN CARDIOVASC THORAC ANN | EUR J CARDIOTHORAC SURG |
| J THORAC CARDIOVASC SURG | ICVTS | ALL CTSNet JOURNALS |