ATS
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow References
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Personal Folders
Right arrow Download to citation manager
Right arrow Author home page(s):
Robert W. Anderson
Juan Rosai
Right arrow Permission Requests
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Vogelzang, N. J.
Right arrow Articles by Kennedy, B. J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Vogelzang, N. J.
Right arrow Articles by Kennedy, B. J.

Ann Thorac Surg 1982;33:333-339
© 1982 The Society of Thoracic Surgeons

Articles

Mediastinal Nonseminomatous Germ Cell Tumors: The Role of Combined Modality Therapy

Nicholas J. Vogelzang, M.D.*, Derek Raghavan, M.B., B.S., Robert W. Anderson, M.D., Juan Rosai, M.D., Seymour H. Levitt, M.D., B.J. Kennedy, M.D.

From the Departments of Medicine (Section of Medical Oncology), Therapeutic Radiology, Laboratory Medicine and Pathology, and Surgery, University of Minnesota Medical School and the Masonic Cancer Center, Minneapolis, MN.

Accepted for publication July 2, 1981.

* Address reprint requests to Dr. Vogelzang, Box 286 Mayo Memorial Building, 420 Delaware St, Minneapolis, MN 55455.

Twelve male patients with mediastinal nonseminomatous germ cell tumors were treated with chemotherapy (with or without operation and radiation therapy) between 1963 and 1980. Eight patients, treated with only chemotherapy and radiotherapy, died with a median survival from diagnosis of 6 months (range, 3 to 12 months). The 4 survivors remain alive at 12, 15, 34, and 56 months from diagnosis; all are without evidence of disease. All surviving patients were treated with surgical resection of disease either before or after chemotherapy. A major problem in the management of mediastinal nonseminomatous germ cell tumors is the persistence of local disease, which may be overcome by vigorous cytoreductive intervention. Multicenter collaboration will be required to define the optimal combined-modality approach.




This article has been cited by other articles:


Home page
 Ann. Thorac. Surg.Home page
D. B. Skinner
Technical and scientific advances in general thoracic surgery
Ann. Thorac. Surg., January 1, 1990; 49(1): 14 - 25.
[PDF]

Home page
 Ann. Thorac. Surg.Home page
P. H. Kay, F. C. Wells, and P. Goldstraw
A Multidisciplinary Approach to Primary Nonseminomatous Germ Cell Tumors of the Mediastinum
Ann. Thorac. Surg., December 1, 1987; 44(6): 578 - 582.
[Abstract] [PDF]

Home page
 Ann. Thorac. Surg.Home page
R. D. Davis Jr., H. N. Oldham Jr., and D. C. Sabiston Jr.
Primary Cysts and Neoplasms of the Mediastinum: Recent Changes in Clinical Presentation, Methods of Diagnosis, Management, and Results
Ann. Thorac. Surg., September 1, 1987; 44(3): 229 - 237.
[Abstract] [PDF]

Home page
 ANN INTERN MEDHome page
N. J. VOGELZANG
Extragonadal Germ-Cell Tumors
Ann Intern Med, December 1, 1982; 97(6): 928 - 929.
[Abstract] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
ANN THORAC SURG ASIAN CARDIOVASC THORAC ANN EUR J CARDIOTHORAC SURG
J THORAC CARDIOVASC SURG ICVTS ALL CTSNet JOURNALS
Copyright © 1982 by The Society of Thoracic Surgeons.