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Ann Thorac Surg 1982;33:234-237
© 1982 The Society of Thoracic Surgeons


Articles

Cardioplegia for Severe Coronary Artery Disease: An Improved Technique Using Direct Coronary Artery Infusion

John G. Coles, M.D., Gregory J. Wilson, M.D.*, Gordon A. Tait, Ph.D., Petr Klement, D.V.M., John C. Coles, M.D., Richard D. Weisel, M.D., Ronald J. Baird, M.D.

From the Cardiovascular Laboratories, Banting Institute, University of Toronto, and the Divisions of Cardiovascular Surgery of the Toronto General Hospital, Toronto, and the Victoria General Hospital, London, Ont, Canada

Accepted for publication March 20, 1981.

* Address reprint requests to Dr. Wilson, Cardiovascular Laboratories, Room 68, Banting Institute, 100 College St, Toronto, Ont, M5G 1L5, Canada

Conventional techniques of cardioplegic solution administration result in regional disparities in the level of myocardial protection in patients with severe coronary artery disease. This report describes a simple adjunct to conventional transaortic administration of cardioplegic solution, in which additional solution is introduced directly through the coronary arteriotomy used for the vein graft anastomosis. The supplemental infusate is delivered through a small-caliber flexible catheter. This technique permits effective perfusion of the coronary vascular bed distal to severely stenotic and occlusive lesions. Using an experimental model of physiologically significant coronary arterial stenosis, we compared the effectiveness of this technique with that of conventional techniques of cardioplegia.




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Improved Myocardial Protection during a Prolonged Cross-Clamp Period
Ann. Thorac. Surg., December 1, 1983; 36(6): 664 - 674.
[Abstract] [PDF]




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