HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) References Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Personal Folders Download to citation manager Author home page(s): Frank P. Catinella Joseph N. Cunningham, Jr. Peter X. Adams Frank C. Spencer Permission Requests Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Catinella, F. P. Articles by Spencer, F. C. Search for Related Content PubMed PubMed Citation Articles by Catinella, F. P. Articles by Spencer, F. C.

Ann Thorac Surg 1982;33:228-233
© 1982 The Society of Thoracic Surgeons

---

Articles

Myocardial Protection with Cold Blood Potassium Cardioplegia during Prolonged Aortic Cross-Clamping

From the Department of Cardiovascular Surgery, New York University School of Medicine, New York, NY

Accepted for publication April 27, 1981.

^* Address reprint requests to Dr. Cunningham, Department of Surgery, New York University Medical Center, Suite 6D, 530 First Ave, New York, NY 10016

The efficacy of cold blood potassium cardioplegia during periods of aortic cross-clamping (greater than 100 minutes) was assessed in 127 patients undergoing a variety of open-heart surgical procedures at New York University Medical Center from January, 1978, to April, 1979. Ischemic intervals ranged from 100 to 267 minutes (mean, 128 minutes). Cardiac-related deaths occurred in only 3 patients (2.4%), and overall operative mortality was 8.7% (11 patients). The rate of perioperative infarction was 10%. Fourteen patients (11%) required vasopressor support or balloon counterpulsation after cardiopulmonary bypass despite the lengthy cross-clamp intervals. Multivariate analysis revealed no significant relationship between the length of cross-clamp time and operative mortality (p = 0.29), incidence of perioperative infarction (p = 0.54), or the occurrence of low-output syndrome postoperatively (p = 0.68). These findings suggest that cold blood potassium cardioplegia provides adequate myocardial protection when periods of arrest as long as 3 to 4 hours are required for complex cardiac surgical procedures.

This article has been cited by other articles:

				T. Asai, E. A. Grossi, M. LeBoutillier III, M. A. Parish, F. G. Baumann, F. C. Spencer, S. B. Colvin, and A. C. Galloway Resuscitative retrograde blood cardioplegiaAre amino acids or continuous warm techniques necessary? J. Thorac. Cardiovasc. Surg., February 1, 1995; 109(2): 242 - 248. [Abstract] [Full Text]

				Y. A. G. Louagie, E. Collard, M. Gonzalez, A. Gruslin, J. Jamart, V. Delire, A. Mayne, M. Buche, and J.-C. Schoevaerdts Initial experience with low-potassium cold blood cardioplegia: A clinical comparative study Ann. Thorac. Surg., April 1, 1992; 53(4): 628 - 634. [Abstract] [PDF]

				Y. Kato, H. Otani, K. Tanaka, Y. Saito, M. Fukunaka, and H. Imamura Effect of cardioplegic preservation on intracellular calcium transients Ann. Thorac. Surg., October 1, 1991; 52(4): 979 - 986. [Abstract] [PDF]

				W. A. Gay Jr Potassium-Induced Cardioplegia: Evolution and Present Status Ann. Thorac. Surg., September 1, 1989; 48(3): 441 - 443. [Abstract] [PDF]

				K. S. Naunheim, A. C. Fiore, D. C. Arango, D. G. Pennington, H. B. Barner, L. R. McBride, H. H. Harris, V. L. Willman, and G. C. Kaiser Coronary artery bypass grafting for unstable angina pectoris: Risk analysis Ann. Thorac. Surg., April 1, 1989; 47(4): 569 - 574. [Abstract] [PDF]

				Y.-F. Chen and Y.-T. Lin Comparison of the Effectiveness of Myocardial Preservation in Right Atrium and Left Ventricle Ann. Thorac. Surg., July 1, 1985; 40(1): 25 - 30. [Abstract] [PDF]

				Y. Morishita and A. Taira Cold Blood Potassium Cardioplegia: A Five-Year Experience With 400 Consecutive Patients Vascular and Endovascular Surgery, May 1, 1985; 19(3): 147 - 154. [Abstract] [PDF]

				Y.-F. Chen and Y.-T. Lin Comparison of Blood Cardioplegia to Electrolyte Cardioplegia on the Effectiveness of Preservation of Right Atrial Myocardium: Mitochondrial Morphometric Study Ann. Thorac. Surg., February 1, 1985; 39(2): 134 - 138. [Abstract] [PDF]

				Y. Morishita and A. Taira Clinical Experience Using Blood Potassium Cardioplegia in valve-Surgery With Prolonged Aortic Cross-Clamp Times Vascular and Endovascular Surgery, September 1, 1984; 18(5): 268 - 272. [Abstract] [PDF]