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Arthur J. Roberts
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John M. Moran
Lawrence L. Michaelis
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Ann Thorac Surg 1981;31:502-511
© 1981 The Society of Thoracic Surgeons

Articles

Nonrandomized Matched Pair Analysis of Intermittent Ischemic Arrest versus Potassium Crystalloid Cardioplegia during Myocardial Revascularization

Arthur J. Roberts, M.D.*, John H. Sanders, Jr., M.D., John M. Moran, M.D., Kerry J. Kaplan, M.D., Peter R. Lichtenthal, M.D., Stewart M. Spies, M.D., Lawrence L. Michaelis, M.D.

Divisions of Cardiothoracic Surgery, Cardiology, and Anesthesia, Northwestern University Medical School, Chicago, IL

Accepted for publication December 10, 1980.

* Address reprint requests to Dr. Roberts, Associate Professor of Surgery, Division of Cardiovascular and Thoracic Surgery, The J. Hillis Miller Health Center, University of Florida, Gainesville, FL 32610

The quest for the ideal method of myocardial preservation during coronary artery bypass graft (CABG) surgery continues at a rapid pace. Nevertheless, in the present clinical practice of cardiac surgery, the choice is chiefly between hypothermic intermittent ischemic arrest and hypothermic potassium cardioplegia. This study applies newer techniques in radionuclear cardiology, as well as more conventional enzymatic, electrocardiographic, and hemodynamic determinations, to the evaluation of the effectiveness of the previously mentioned modes of myocardial protection. Serial assessments are made preoperatively as well as during the first ten days postoperatively. We find that the perioperative incidence of myocardial damage and changes in left ventricular performance are almost identical using either method in patients with relatively normal preoperative left ventricular performance who do not have severe preoperative refractory ischemia or necrosis.




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 Ann. Thorac. Surg.Home page
S. V. Moran, B. Chuaqui, M. J. Irarrazaval, P. Thomsen, M. Navarro, J. Urzua, and G. Maturana
Ultrastructural Myocardial Preservation During Coronary Artery Surgery: A Controlled, Prospective, Randomized Study in Humans
Ann. Thorac. Surg., January 1, 1986; 41(1): 79 - 84.
[Abstract] [PDF]

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 Ann. Thorac. Surg.Home page
A. J. Roberts, J. M. Moran, J. H. Sanders, S. M. Spies, P. R. Lichtenthal, K. J. Kaplan, and L. L. Michaelis
Clinical Evaluation of the Relative Effectiveness of Multidose Crystalloid and Cold Blood Potassium Cardioplegia in Coronary Artery Bypass Graft Surgery: A Nonrandomized Matched-Pair Analysis
Ann. Thorac. Surg., May 1, 1982; 33(5): 421 - 433.
[Abstract] [PDF]


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