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Ann Thorac Surg 1981;31:373-376
© 1981 The Society of Thoracic Surgeons

Articles

Contractile Fibroblasts (Myofibroblasts) in a Painful Pacemaker Pocket

Ross Rudolph, M.D., Joe R. Utley, M.D.*, Marilyn Woodward, B.S.

Divisions of Plastic and Cardiothoracic Surgery, Veterans Administration Medical Center, and University of California, San Diego, CA

Accepted for publication March 24, 1980.

* Address reprint requests to Dr. Utley, 225 W Dickinson St, San Diego, CA 92103

Electron microscopy of a painful fibrotic capsule around a cardiac pacemaker revealed classic myofibroblasts. These contractile fibroblasts share characteristics of both smooth muscle cells and fibroblasts and are thought to be the cellular cause of wound and scar contraction. The occurrence of pain and tenderness around a sterile pacemaker probably indicates contraction of scar tissue as the basis of the symptoms. This scar tissue is similar to that seen around other large inert implants placed in the thoracic tissue.




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Home page
 Ann. Thorac. Surg.Home page
R. Rudolph, M. R. Smith, and G. P. Curtis
Salvage of Pacemakers and Automatic Implantable Cardioverter-Defibrillators Using Dermis Grafts
Ann. Thorac. Surg., February 1, 2011; 91(2): 452 - 456.
[Abstract] [Full Text] [PDF]


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