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The Annals of Thoracic Surgery, Vol 31, 357-359, Copyright © 1981 by The Society of Thoracic Surgeons
F Robicsek, TN Masters, L Littman and GV Born
We discuss our study on the effects of discontinuation of the usage of bone
wax as a hemostatic agent in sternotomy incisions. In 1976, we abandoned
use of bone wax because it was suspected of causing several cases of
Mycobacterium fortuitum sternal osteomyelitis. In a retrospective study
involving 400 patients, we found that this step did not increase
postoperative bleeding as measured by drainage from the chest tube and by
the need to return patients to the operating room because of bleeding. It
also was observed that there was an appreciable simultaneous drop in
pulmonary complications. To test our theory that the wax pressed into the
bone marrow can embolize to the lung, radioactively tagged bone wax was
pressed into the cut sternum in animal models, and a search was made for
radioactive deposits in the peripheral lung tissue. Shortly after the
application of the wax, there was evidence of large radioactive deposits in
the lungs. It is probable that this embolization occurs also under clinical
conditions and may play a role in pulmonary complications following
open-heart operations.
ARTICLES
The embolization of bone wax from sternotomy incisions
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