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Ann Thorac Surg 1980;30:584-587
© 1980 The Society of Thoracic Surgeons
From the Department of Pathology, State University of Utrecht, and St. Antonius Hospital, Utrecht, and the Wilhelmina Gasthuis, University of Amsterdam, Amsterdam, The Netherlands
Accepted for publication January 9, 1980.
* Address reprint requests to Dr. Elbers, Department of Pathology, State University of Utrecht, Pasteurstraat 2, Utrecht, The Netherlands
Two patients with massive, tumorsimulating extramedullary hematopoiesis are presented. In 1 patient with homozygous β-thalassemia, a progressive paraparesis developed because of a mass of ectopic marrow in the spinal epidural space. Surgical removal and radiotherapy were successful. The second patient, who died during surgical biopsy, had posterior mediastinal masses without any apparent cause. A correct preoperative diagnosis may avoid unnecessary surgical intervention. It is suggested that heterotopic marrow should be included in the differential diagnosis of a mass in the lower thoracic region.
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