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Ann Thorac Surg 1980;30:550-557
© 1980 The Society of Thoracic Surgeons

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Articles

Aortocoronary Bypass with Homologous Saphenous Vein: Long-Term Results

From the Department of Cardiovascular Surgery, C. M. C. Foch-Université Paris-Ouest, Suresnes, and the Department of Pathology, Hôpital Broussais, Paris, France

^* Address reprint requests to Dr. Bical, Department of Cardiovascular Surgery, C. M. C. Foch, 40, rue Worth, 92151–Suresnes, France

Between February, 1973, and February, 1979, 27 homologous saphenous veins were used in 20 patients (mean age, 54 years). Seven fresh grafts were used less than 24 hours after severance. They were kept at a temperature of 4°C in saline solution containing penicillin. Twenty cryopreserved grafts were used within a period of eight days to 2 months from severance. They were preserved in glycerol at a temperature of –40°C.

One patient (5%) died postoperatively. A perioperative myocardial infarction developed in 3 patients (15%). Average follow-up is 27 months. No late mortality was registered. Fifteen patients are free from symptoms, and 3 patients have residual angina with exercise.

Control angiograms were made in 13 patients 1 to 68 months after operation; 17 homografts were seen. Early occlusion of 1 graft and late occlusion of 8 grafts were registered.

The poor late patency rate does not seem to be related to either histocompatibility or technical conditions. Conversely, microscopic examination of several cryopreserved grafts showed that the mode of preservation resulted in deterioration of intimal and medial tissues of the vein. Therefore, it appears to us that the use of homologous saphenous veins should be avoided for coronary bypass.

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