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Ann Thorac Surg 1980;30:285-290
© 1980 The Society of Thoracic Surgeons


Articles

An Improved Technique for Producing Ventricular Hypertrophy with a Subcoronary Valvular Aortic Stenosis Model

James D. Sink, M.D.*, David E. Attarian, M.D., W.R. Chitwood, Jr., M.D., Ronald C. Hill, M.D., Gary L. Pellom, B.S., Andrew S. Wechsler, M.D.

From the Departments of Surgery, Duke University Medical Center and the Veterans Administration Hospital, Durham, NC

Accepted for publication January 30, 1980.

* Address reprint requests to Dr. Sink, P.O. Box 3426, Department of Surgery, Duke University Medical Center, Durham, NC 27710

Although techniques for producing aortic valve stenosis proximal to the ostia of the coronary arteries have been described in experimental animals, only moderate left ventricular hypertrophy has been obtained. A technique for plicating the noncoronary sinus of Valsalva in puppies is presented that has enabled us to achieve levels of ventricular hypertrophy not previously reported with methods for subcoronary aortic stenosis.




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G. J. Grover, P. M. Scholz, J. W. Mackenzie, and H. R. Weiss
Effect of Aortic Stenosis on Oxygen Balance in Partially Ischemic Myocardium
Ann. Thorac. Surg., March 1, 1987; 43(3): 270 - 275.
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Ann. Thorac. Surg.Home page
J. D. Sink, R. C. Hill, D. E. Attarian, and A. S. Wechsler
Myocardial Blood Flow and Oxygen Consumption in the Empty-Beating, Fibrillating, and Potassium-Arrested Hypertrophied Canine Heart
Ann. Thorac. Surg., April 1, 1983; 35(4): 372 - 379.
[Abstract] [PDF]




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Copyright © 1980 by The Society of Thoracic Surgeons.