The Annals of Thoracic Surgery, Vol 30, 285-290, Copyright © 1980 by The Society of Thoracic Surgeons
An improved technique for producing ventricular hypertrophy with a subcoronary valvular aortic stenosis model
JD Sink, DE Attarian, WR Chitwood Jr, RC Hill, GL Pellom and AS Wechsler
Although techniques for producing aortic valve stenosis proximal to the
ostia of the coronary arteries have been described in experimental animals,
only moderate left ventricular hypertrophy has been obtained. A technique
for plicating the noncoronary sinus of Valsalva in puppies is presented
that has enabled us to achieve levels of ventricular hypertrophy not
previously reported with methods for subcoronary aortic stenosis.