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Ann Thorac Surg 1980;30:52-57
© 1980 The Society of Thoracic Surgeons

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Articles

A Comparison of the Effects of Membrane and Bubble Oxygenators on Platelet Counts and Platelet Size in Elective Cardiac Operations

From the Department of Surgery, University of Minnesota, Minneapolis, MN

Accepted for publication December 14, 1979.

^* Address reprint requests to Dr. Trumbull, Division of Cardiac Surgery, University of Arkansas for Medical Sciences, 4301 W Markham St, Little Rock, AR 72205

To compare the effects of membrane and bubble oxygenators on platelet counts and the size of circulating platelets, serial hematocrits, platelet counts, and platelet sizing were measured in 23 patients undergoing elective cardiac operations. In 10 patients a bubble oxygenator was used and in 13, a SciMed membrane oxygenator. The two groups were statistically similar with respect to age, weight, time on bypass, and mean blood flow rates during bypass.

It was found that platelet counts, when corrected for hemodilution, did not fall from control levels during or up to 24 hours after cardiopulmonary bypass in either group. In both groups, the relative number of platelets per gram of hemoglobin increased slightly during and after bypass, and this increase was significant in the bubble oxygenator group. The average size of circulating platelets increased only in the bubble oxygenator group, and then only in the one-day postoperative sample. These findings suggest that the membrane oxygenator offers no advantage with respect to preservation of platelets during cardiopulmonary bypass lasting up to 2 to 3 hours.

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				D. T Pearson, B. McArdle, S. J Poslad, and A. Murray A clinical evaluation of the performance characteristics of one membrane and five bubble oxygenators: haemocompatibility studies Perfusion, January 1, 1986; 1(2): 81 - 98. [Abstract] [PDF]