ATS
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow References
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Personal Folders
Right arrow Download to citation manager
Right arrow Author home page(s):
William H. Prioleau, Jr.
Right arrow Permission Requests
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Voegele, L. D.
Right arrow Articles by Hairston, P.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Voegele, L. D.
Right arrow Articles by Hairston, P.

Ann Thorac Surg 1980;29:444-450
© 1980 The Society of Thoracic Surgeons

Articles

Application of Multivariate Analysis to the Enzyme Patterns in the Serum of Patients Undergoing Coronary Artery Operation

L. Dieter Voegele, M.D.*, Alan J. Gross, Ph.D., William H. Prioleau, Jr., M.D., Peter Hairston, M.D.

Division of Thoracic and Cardiovascular Surgery and the Department of Biometry, Medical University of South Carolina, Charleston, SC

Accepted for publication November 28, 1979.

* Address reprint requests to Dr. Voegele, Suite 1-H, Ashley House, Charleston, SC 29401

Serial determinations of serum glutamic oxaloacetic transaminase, lactic dehydrogenase, and creatine phosphokinase were performed in 50 consecutive patients undergoing cardiac operation for coronary artery bypass or combined valve replacement and coronary artery bypass. Thirty-seven patients (74%) who demonstrated minimal or no changes on the electrocardiogram manifested a recognizable pattern of distribution of the enzyme sequences. The pattern of these patients served as controls for the detection of abnormal patterns. All other patients were grouped together, regardless of clinical behavior. Perioperative myocardial infarction was established in 5 patients (10%) and resulted in 1 death. The purpose of this study was to apply discriminant analysis to two clinically determined patient groups in order to ascertain whether the three enzyme readings can be used to classify patients into their respective groups. The results suggest that enzyme profiles reflect degrees of myocardial damage that can serve to identify clinical infarction.






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
ANN THORAC SURG ASIAN CARDIOVASC THORAC ANN EUR J CARDIOTHORAC SURG
J THORAC CARDIOVASC SURG ICVTS ALL CTSNet JOURNALS
Copyright © 1980 by The Society of Thoracic Surgeons.