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Ann Thorac Surg 1980;29:378-380
© 1980 The Society of Thoracic Surgeons

Articles

Propranolol: An Unrecognized Cause of Central Nervous System Dysfunction in Patients Undergoing Cardiopulmonary Bypass

Abraham Lieberman, M.D.*, Itzhak Kronzon, M.D., Stephen Colvin, M.D., Jerome Lowenstein, M.D., Ina Lieberman, M.D.

New York University School of Medicine, New York, NY

Accepted for publication July 20, 1979.

* Address reprint requests to Dr. Lieberman, 530 First Ave, Suite 5A, New York, NY 10016

An organic mental syndrome developed in a patient soon after he underwent repair of a dissecting thoracic aortic aneurysm. The operation was accomplished with cardiopulmonary bypass. Initially, the mental changes were thought to be related to the operation. However, they subsequently were shown to be associated with propranolol. The potential role of propranolol in inducing central nervous system disturbances is emphasized, and the literature on the subject is reviewed.






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