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Ann Thorac Surg 1980;29:8-14
© 1980 The Society of Thoracic Surgeons

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Articles

MB Creatine Kinase and the Evaluation of Myocardial Injury Following Aortocoronary Bypass Operation

Montreal Heart Institute, Montreal, Que, Canada

Accepted for publication February 27, 1979.

^* Address reprint requests to Dr. Maillé, Montreal Heart Institute, 5000 East, Belanger Street, Montreal, Que, H1T 1C8, Canada

Myocardial injury was studied in 104 patients undergoing coronary artery grafting without cold chemical cardioplegia using the quantity of the isoenzyme MB of the creatine kinase liberated as an indicator. This method of evaluation, which is said to permit comparison of different techniques of myocardial protection, allowed us to consider the relative importance of several factors believed to have an influence on intraoperative myocardial injury. Indices of significance were duration of symptoms before operation, presence of chronic arterial hypertension, and the type of antiangina treatment employed. Other operative factors included severity of the arterial lesions, number of anastomoses performed, and duration of extracorporeal circulation and of aortic cross-clamping.

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