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The Annals of Thoracic Surgery, Vol 29, 70-73, Copyright © 1980 by The Society of Thoracic Surgeons

ARTICLES

Use of nitroprusside for control of pulmonary hypertension in repair of ventricular septal defect

PA Faraci, HF Rheinlander and RJ Cleveland

After repair of ventricular septal defect (VSD) in a 3-year-old child with markedly elevated pulmonary vascular resistance (PVR), sodium nitroprusside was administered by intravenous infusion at 3.0 microgram per kilogram of body weight per minute. Nitroprusside was effective in reducing pulmonary artery pressure and increasing systemic blood pressure in the intraoperative and early post-operative periods. It is suggested that nitroprusside may facilitate the perioperative management and enhance the early survival in patients with increased PVR secondary to a VSD.




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Copyright © 1980 by The Society of Thoracic Surgeons.