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Ann Thorac Surg 1979;28:436-439
© 1979 The Society of Thoracic Surgeons

Articles

Prospective Analysis of Heart Biopsies in Coronary Artery Surgery

Tomas A. Salerno, M.D.*, Santosh M. Wasan, M.B.B.S., Edward J.P. Charrette, M.D.

From the Departments of Surgery and Pathology, Queen's University, Kingston, Ont, Canada.

Accepted for publication December 6, 1978.

* Address reprint requests to Dr. Salerno, Department of Surgery, Queen's University, Kingston, Ont, Canada.

In a prospective analysis of 36 biopsies from human hearts performed at the time of elective coronary operation, several morphological changes were identified in the myocardium. Some of these changes (fibrosis, vacuolation, edema, and amyloid deposition) are of clinical significance and may affect the long-term prognosis for patients undergoing revascularization procedures. It appears, therefore, that knowledge of the morphological state of the myocardium at the time of operation can prove useful in elucidating further the long-term effects of coronary artery bypass on the left ventricular myocardium.




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