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Ann Thorac Surg 1979;28:363-368
© 1979 The Society of Thoracic Surgeons

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Articles

Treatment of Inoperable Lung Carcinoma: A Combined Modality Approach

Department of Thoracic Surgery, Roswell Park Memorial Institute, Buffalo, the Department of Medicine, George Washington University, Washington, DC, and the Surgical Service, Veterans Administration Hospital, Buffalo, NY.

^* Address reprint requests to Dr. Takita, Department of Thoracic Surgery, Roswell Park Memorial Institute, 666 Elm St, Buffalo, NY 14263.

Twenty-four patients with inoperable lung carcinoma other than of the small cell type who received cis diamminedichloro platinum (II)-based combination chemotherapy were further treated with all available treatment modalities: radiation therapy, lung resection, chemotherapy, and immunotherapy. There were 2 operative deaths, and 2 patients died 6 and 8 months postoperatively of cardiac causes. Postmortem examination on these 4 patients revealed no evidence of residual tumor. The remaining 20 patients are alive 7 to 33 months from the onset of chemotherapy and 4 to 27 months following lung resection. These results, although preliminary, are encouraging, and further study is in progress.

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