HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Personal Folders Download to citation manager Permission Requests Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Landymore, R. W. Articles by Qirbi, A. A. Search for Related Content PubMed PubMed Citation Articles by Landymore, R. W. Articles by Qirbi, A. A.

The Annals of Thoracic Surgery, Vol 28, 261-268, Copyright © 1979 by The Society of Thoracic Surgeons

ARTICLES

Does pulsatile flow influence the incidence of postoperative hypertension?

RW Landymore, DA Murphy, CE Kinley, JC Parrott, EA Moffitt, WJ Longley and AA Qirbi

Twenty patients undergoing primary elective aorta--coronary artery bypass were divided into two equal groups, both receiving identical premedication, anesthetic, and pump primes. The control patients received hypothermic nonpulsatile flow and the study patients received hypothermic pulsatile flow. Hypertension, defined as a pressure of 160/100 mm Hg or higher, was observed in 80% of the control patients and 20% of the patients receiving pulsatile flow (p less than 0.05). Serial renin measurements demonstrated maximum values in the intensive care unit and coincided with the onset of postoperative hypertension in the control patients. Those patients who had received pulsatile flow did not demonstrate notable renin stimulation. Catecholamines were markedly elevated during bypass and in the intensive care unit, but there was no significant difference between the two groups. Peripheral vascular resistance was not significantly lower with pulsatile flow, except in the first study performed in the intensive care unit. We conclude that catecholamines and the renin-angiotensin system contribute to the production of postoperative hypertension and that pulsatile flow diminishes renin stimulation. Pulsatile flow results in a decreased incidence of postoperative hypertension.

This article has been cited by other articles:

				F. Onorati, L. Cristodoro, P. Mastroroberto, A. di Virgilio, A. Esposito, M. Bilotta, and A. Renzulli Should We Discontinue Intraaortic Balloon During Cardioplegic Arrest? Splanchnic Function Results of a Prospective Randomized Trial Ann. Thorac. Surg., December 1, 2005; 80(6): 2221 - 2228. [Abstract] [Full Text] [PDF]

				M. Ingyinn, K. Rais-Bahrami, R. Evangelista, I. Hogan, O. Rivera, G. T Mikesell, and B. L Short Comparison of the effect of venovenous versus venoarterial extracorporeal membrane oxygenation on renal blood flow in newborn lambs Perfusion, May 1, 2004; 19(3): 163 - 170. [Abstract] [PDF]

				E. Silistreli, H. Catalyurek, N. Sariosmanoglu, U. Acikel, E. Hazan, and O. Oto Effects on the Endocrine System of Pulsatile and Nonpulsatile Perfusion in Heart Surgery Asian Cardiovasc Thorac Ann, March 1, 1999; 7(1): 18 - 22. [Abstract] [Full Text] [PDF]

				C. Vedrinne, F. Tronc, S. Martinot, J. Robin, C. Garhib, J. Ninet, J. J. Lehot, M. Franck, and G. Champsaur Effects of various flow types on maternal hemodynamics during fetalbypass: Is there nitric oxide release during pulsatile perfusion? J. Thorac. Cardiovasc. Surg., September 1, 1998; 116(3): 432 - 436. [Abstract] [Full Text]

				S. Ohri and P. Abel Review article : The pathophysiology of nephrourological complications following cardiopulmonary bypass Perfusion, April 1, 1991; 6(2): 79 - 91. [PDF]

				P. J. A. van der Starre, R. S. Reneman, and H. W. Scheijgrond Ketanserin in the Treatment of Systemic Hypertension During and Following Coronary Artery Bypass Surgery Angiology, November 1, 1989; 40(11): 1001 - 1010. [Abstract] [PDF]