ATS
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
 QUICK SEARCH:   [advanced]


     


This Article
Right arrow Full Text (PDF)
Right arrow References
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Personal Folders
Right arrow Download to citation manager
Right arrow Author home page(s):
Jack A. Roth
Ramon A. Cukingnan
Calvin R. Scott
Right arrow Permission Requests
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Roth, J. A.
Right arrow Articles by Scott, C. R.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Roth, J. A.
Right arrow Articles by Scott, C. R.

Ann Thorac Surg 1979;28:69-72
© 1979 The Society of Thoracic Surgeons


Articles

Use of Activated Coagulation Time to Monitor Heparin during Cardiac Surgery

Jack A. Roth, M.D., Ramon A. Cukingnan, M.D.*, Calvin R. Scott, B.S.

From the Department of Thoracic Surgery, Wadsworth Veterans Administration Hospital and UCLA Medical Center, Los Angeles, CA

Accepted for publication November 1, 1978.

* Address reprint requests to Dr. Cukingnan, 112G Wadsworth VA Hospital, Wilshire and Sawtelle Blvds, Los Angeles, CA 90073

Activated coagulation time (ACT) for protamine reversal was monitored in 28 consecutive patients (Group 1) and a standard heparin-protamine protocol was used for an earlier series of 28 patients (Group 2). Although Group 1 received a significantly higher total heparin dose than Group 2 (p < 0.01), the protamine dose for reversal was significantly less for the ACT group than for the controls (p < 0.0005). The mean ratio of protamine to total heparin was 1:1 (range, 0.33 to 1.44) for the ACT group and 2:1 (range, 1.42 to 2.59) for the controls. There were no significant differences between the two groups in operative and postoperative blood loss, transfusion requirements, hematocrit, and partial thromboplastin time. This study shows that the ACT test did not reduce postoperative bleeding significantly when compared with our standard protocol. It also indicates that there is wide individual sensitivity to heparin and that significantly less protamine is required for reversal.




This article has been cited by other articles:


Home page
Br J AnaesthHome page
L. J. Enriquez and L. Shore-Lesserson
Point-of-care coagulation testing and transfusion algorithms
Br. J. Anaesth., December 1, 2009; 103(suppl_1): i14 - i22.
[Abstract] [Full Text] [PDF]


Home page
Ann. Thorac. Surg.Home page
The Society of Thoracic Surgeons Blood Conservatio, V. A. Ferraris, S. P. Ferraris, S. P. Saha, E. A. Hessel II, C. K. Haan, B. D. Royston, C. R. Bridges, R. S.D. Higgins, G. Despotis, et al.
Perioperative Blood Transfusion and Blood Conservation in Cardiac Surgery: The Society of Thoracic Surgeons and The Society of Cardiovascular Anesthesiologists Clinical Practice Guideline
Ann. Thorac. Surg., May 1, 2007; 83(5_Supplement): S27 - S86.
[Abstract] [Full Text] [PDF]


Home page
Clin. Chem.Home page
G. J. Despotis, J. H. Joist, and L. T. Goodnough
Monitoring of hemostasis in cardiac surgical patients: impact of point-of-care testing on blood loss and transfusion outcomes
Clin. Chem., September 1, 1997; 43(9): 1684 - 1696.
[Abstract] [Full Text] [PDF]


Home page
PerfusionHome page
C. Aren
Review article : Heparin and protamine during cardiac surgery
Perfusion, July 1, 1989; 4(3): 171 - 181.
[PDF]


Home page
Ann. Thorac. Surg.Home page
T. L. Winton, E. J. P. Charrette, and T. A. Salerno
The Cell Saver during Cardiac Surgery: Does It Save?
Ann. Thorac. Surg., April 1, 1982; 33(4): 379 - 381.
[Abstract] [PDF]


Home page
Ann. Thorac. Surg.Home page
W. S. Stoney, W. C. Alford Jr., G. R. Burrus, D. M. Glassford Jr., and C. S. Thomas Jr.
Air Embolism and Other Accidents Using Pump Oxygenators
Ann. Thorac. Surg., April 1, 1980; 29(4): 336 - 340.
[Abstract] [PDF]




HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
ANN THORAC SURG ASIAN CARDIOVASC THORAC ANN EUR J CARDIOTHORAC SURG
J THORAC CARDIOVASC SURG ICVTS ALL CTSNet JOURNALS
Copyright © 1979 by The Society of Thoracic Surgeons.