The Annals of Thoracic Surgery, Vol 28, 14-21, Copyright © 1979 by The Society of Thoracic Surgeons
Clinical experience with the isotopic cardiac pacemaker
NP Smyth, JD Keshishian, JM Garcia, LC Kelly and D Proctor
Clinical experience with isotopic pacemakers in 59 patients is compared
with that in 77 control patients having conventional chemical battery-
powered pulse generators. The review covers a 51/2-year period. Statistical
analysis of the two series is impossible because of the numerous variables
such as age, type of disease, number of controls, types of test and control
pulse generators, dates of insertion, and protocol regulations. However,
there were pulse generator failures in the control group, but not in the
test group. Though not proven in this study, the isotopic cardiac pacer is
likely to last longer than conventional chemical battery-powered units, and
could provide lifetime pacing for many patients. The risk of carcinogenesis
is minimal and seems negligible in older patients. The isotopic cardiac
pacer, in spite of restrictions of the Nuclear Regulatory Commission,
should be considered for any patient with a life expectancy of 10 or more
years. Paradoxically, it might be indicated in older rather than younger
patients.