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Ann Thorac Surg 1979;27:320-327
© 1979 The Society of Thoracic Surgeons

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Articles

Combined Multiple-Valve Procedures: A Five-Year Experience with 125 Patients

Department of Surgery, Division of Thoracic and Cardiovascular Surgery, University of Iowa Hospitals and Clinics, Iowa City, IA

Accepted for publication September 14, 1978.

^* Address reprint requests to Dr. Wright, Division of Thoracic and Cardiovascular Surgery, University of Iowa Hospitals and Clinics, Iowa City, IA 52242

One hundred twenty-five patients underwent 128 operations for combined multiple-valve procedures, with an overall early mortality of 16%. Highest mortality was associated with mitral and tricuspid valve disease (28.5%), followed by triple-valve disease (18.2%) and aortic and mitral valve disease (14%). Left ventricular end-diastolic pressure, cardiac index, mean pulmonary artery pressure, pulmonary artery wedge pressure, and arteriovenous oxygen difference were all significantly different in patients with regard to early mortality.

Late follow-up of 94% has been achieved in 105 early survivors, with a late mortality rate of 11.2%. Analysis of late functional results reveal that 85% of survivors improved at least one Functional Class. Actuarial 5-year survival of 75% was achieved for early survivors of operation.

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