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Ann Thorac Surg 1979;27:295-299
© 1979 The Society of Thoracic Surgeons


Articles

The Role of Thoracotomy in the Management of Pulmonary Metastases from Malignant Melanoma

Douglas J. Mathisen, M.D.*, M. Wayne Flye, M.D., Joseph Peabody, M.D.

Surgery Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD

* Address reprint requests to Dr. Mathisen, Surgery Branch, NCI, Building 10, Room 10N116, National Institutes of Health, Bethesda, MD 20014

Thirty-three patients over a 21-year period underwent thoracotomy for resection of suspected pulmonary metastases from malignant melanoma. Eleven patients were found to have nonmalignant disease (Group 1); 10 were found to have unresectable disease (Group 2); and 12 were rendered disease-free (Group 3). Of the patients found to have melanoma, 20 of 22 received postoperative chemotherapy. The median survival of the patients in Group 2 was 10.5 months (3 to 20 months); in Group 3 it was 12 months (3 to 35 months). There were no 5-year survivors. No factors distinguished the three groups preoperatively. Surgical resection still offers the greatest chance for long-term survival, based on reports of patients in the literature who have survived longer than 5 years following resection of pulmonary metastases from melanoma. Thoracotomy is especially useful for staging purposes in those patients found to have no metastatic disease.




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