HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) References Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Personal Folders Download to citation manager Author home page(s): Dennis L. Modry Ray Chu-Jeng Chiu Permission Requests Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Modry, D. L. Articles by Chiu, R. C.-J. Search for Related Content PubMed PubMed Citation Articles by Modry, D. L. Articles by Chiu, R. C.-J.

Ann Thorac Surg 1979;27:206-215
© 1979 The Society of Thoracic Surgeons

---

Articles

Pulmonary Reperfusion Syndrome

Division of Cardiovascular and Thoracic Surgery, McGill University and Montreal General Hospital, Montreal, Que, Canada

Accepted for publication July 28, 1978.

^* Address reprint requests to Dr. Chiu, Montreal General Hospital, 1650 Cedar Ave, Montreal, Que, Canada H3G 1A4

"Reperfusion syndrome" of the lung may play a role in the pulmonary edema and hemorrhage that occur following pulmonary embolectomy, cardiopulmonary bypass, and shock. Bioenergetic, metabolic, and ultrastructural studies of canine lungs indicate that ventilated lung tissue could tolerate 5 hours of pulmonary arterial occlusion with minimal damage. However, a 24-hour interruption of pulmonary arterial blood flow produced a significant decrease in the ratio of adenosine triphosphate to adenosine diphosphate, and glycogen, and an increase in tissue lactate. Reperfusion of these lungs resulted in even more pronounced biochemical and ultrastructural deterioration, as well as gross pulmonary edema and hemorrhage. The lesion appears to be similar to the reperfusion damage that occurs in other organs, such as the kidney, and the skeletal and cardiac muscles.

This article has been cited by other articles:

				B. Koul, H. Willen, T. Sjoberg, T. Wetterberg, J. Kugelberg, and S. Steen Pulmonary sequelae of prolonged total venoarterial bypass: Evaluation with a new experimental model Ann. Thorac. Surg., May 1, 1991; 51(5): 794 - 799. [Abstract] [PDF]