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Ann Thorac Surg 1979;27:141-143
© 1979 The Society of Thoracic Surgeons

Articles

Myocardial Hypertrophy: The Distribution of Cell Growth within the Layers of the Myocardium

Tomas A. Salerno, F.R.C.S.(C)*, Harry M. Shizgal, M.D., Anthony R.C. Dobell, M.D.

From the Departments of Surgery, Royal Victoria Hospital and McGill University, Montreal, Que, Canada

Accepted for publication May 12, 1978.

* Address reprint requests to Dr. Salerno, Department of Surgery, Queen's University, Kingston, Ont, Canada K7L 2V7

The spatial distribution of radioactively labeled microspheres was studied in normal and in experimentally hypertrophied hearts of adult pigs. The hearts had been "tagged" with microspheres when the pigs were young. When the adult animal was killed, the spatial distribution of the microspheres was identical in the normal and in the hypertrophied hearts. This demonstrates that hypertrophic growth had occurred evenly throughout all layers of the myocardium.




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T. A. Salerno and M. A. Chiong
Ventricular Fibrillation Induced Prior to Cardioplegic Arrest in Hypertrophied Pig Hearts
Ann. Thorac. Surg., August 1, 1983; 36(2): 152 - 160.
[Abstract] [PDF]


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