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Ann Thorac Surg 1979;27:86
© 1979 The Society of Thoracic Surgeons

Articles

Drug Delivery

Ellwood G. Voorhees, CPT, Walter H. Brott, COL, Thomas E. Bowen, COL, all, MC, USA*

Thoracic-Cardiovascular Surgery Service, Walter Reed Army Medical Center, Washington, DC.

Accepted for publication February 15, 1978.

* Address reprint requests to Dr. Bowen, Box 327, Letterman Army Medical Center, Presidio of San Francisco, CA 94129.

The calculations necessary to allow infusion of a known drug dosage at micrograms per kilogram of body weight per minute are time-consuming and error prone. A simpler method entails multiplication of the patient's weight in kilograms by the factor 15. The resultant figure represents the number of milligrams of drug to be placed in 250 ml of infusate vehicle. The solution, which is delivered through a microdrip chamber (60 gtt per milliliter), will contain 1 µg per kilogram in each drop. One is thus permitted to define dosage by setting up the solution to have 1 gtt = 1 µg/kg.






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