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Ann Thorac Surg 1978;26:485-487
© 1978 The Society of Thoracic Surgeons

Articles

Maintenance of Permanently Implanted Cardiac Pressure Catheters in Experimental Animals

W. Randolph Chitwood, Jr., M.D.*, Ronald C. Hill, M.D., Andrew S. Wechsler, M.D.

Department of Surgery, Duke University Medical Center, Durham, NC.

Accepted for publication January 13, 1978.

* Address reprint requests to Dr. Chitwood, Box 3025, Department of Surgery, Duke University Medical Center, Durham, NC 27710.

Two techniques for maintaining permanently implanted cardiac catheters in experimental animals are described. Polyvinylchloride catheters are coated with TDMAC-Heparin, a polymer complex currently used clinically to prevent thrombogenesis in vascular shunts. Long-term catheter obstruction and thrombus formation have been obviated by using this method. Also, to assure multiple, painless studies in awake animals, a somewhat different technique for pressure catheter access has been developed and is detailed in this report.






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Copyright © 1978 by The Society of Thoracic Surgeons.