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Ann Thorac Surg 1978;26:149-154
© 1978 The Society of Thoracic Surgeons

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Articles

Heterologous Pericardium for the Closure of Pericardial Defects

Cirugia Cardiovascular, Centro Medico Valdecilla, Cirugia Experimental, Facultad de Medicina, Universidad de Santander, Santander, Spain

^* Address reprint requests to Dr. Gallo, Servicio de Cirugia Cardiovascular, Centro Medico Nacional "Marques de Valdecilla," Santander, Spain

Patches of glutaraldehyde-preserved porcine pericardium were transplanted orthotopically into 20 dogs to see if they might make a satisfactory pericardial substitute. Two dogs had mediastinal infections and were excluded from this study. All animals were reoperated on at regular intervals between 15 and 300 days. In 15 dogs there were no adhesions between the porcine pericardium and the host's epicardium. Histological study showed healing between both pericardiums and no degenerative changes in transplanted pericardium. Glutaraldehyde porcine pericardium has been utilized in 8 patients to close the pericardial cavity. There have been no problems related to the pericardial grafts after a maximum follow-up of 9 months.

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