| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
Ann Thorac Surg 1978;25:259-271
© 1978 The Society of Thoracic Surgeons
Department of Surgery, University of California—Moffitt Hospital, San Francisco, CA 94143.
Pulsatile and nonpulsatile blood flow have been intensely studied for cardiopulmonary bypass (CPB), isolated organ perfusion, and myocardial preservation. Although early studies differed, later ones have shown the benefits of pulsatile flow. Kidney function, lymph flow, and oxygen consumption are increased during pulsatile perfusion. Also, nonpulsatile CPB increases total peripheral resistance and mean arterial pressure, which are related to time of perfusion. Theories to account for the superiority of pulsatile flow include: (1) "vascular shocks" causing physical displacement of tissues, which changes the boundary layer of interstitial fluid around cell membranes and enhances diffusion; (2) increased lymph movement during pulsatile flow; and (3) pulsatile energy ensuring the patency of the vascular beds and preventing shunting. New methods to create pulsatile flow and their adaptation to the standard roller pump are discussed.
This article has been cited by other articles:
|
|
 |
|
  B. Voss, M. Krane, C. Jung, G. Brockmann, S. Braun, T. Gunther, R. Lange, and R. Bauernschmitt Cardiopulmonary bypass with physiological flow and pressure curves: pulse is unnecessary! Eur J Cardiothorac Surg, January 1, 2010; 37(1): 223 - 232. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 G. S. Murphy, E. A. Hessel II, and R. C. Groom Optimal Perfusion During Cardiopulmonary Bypass: An Evidence-Based Approach Anesth. Analg., May 1, 2009; 108(5): 1394 - 1417. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. Ovroutski, P. Ewert, V. Alexi-Meskishvili, K. Holscher, O. Miera, B. Peters, R. Hetzer, and F. Berger Absence of Pulmonary Artery Growth After Fontan Operation and Its Possible Impact on Late Outcome Ann. Thorac. Surg., March 1, 2009; 87(3): 826 - 831. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 H. N Mayrovitz Interface Pressures Produced by Two Different Types of Lymphedema Therapy Devices Physical Therapy, October 1, 2007; 87(10): 1379 - 1388. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 B. Ji and A. Undar Review Article: Comparison of perfusion modes on microcirculation during acute and chronic cardiac support: is there a difference? Perfusion, March 1, 2007; 22(2): 115 - 119. [Abstract] [PDF]
|
|
|
|
 |
|
 G. S. Kassab, M. Kostelec, G. D. Buckberg, J. Covell, A. Sadeghi, and J. I.E. Hoffman Myocardial protection in the failing heart: II. Effect of pulsatile cardioplegic perfusion under simulated left ventricular restoration J. Thorac. Cardiovasc. Surg., October 1, 2006; 132(4): 884 - 890. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. Loutzenhiser, K. Griffin, G. Williamson, and A. Bidani Renal autoregulation: new perspectives regarding the protective and regulatory roles of the underlying mechanisms Am J Physiol Regulatory Integrative Comp Physiol, May 1, 2006; 290(5): R1153 - R1167. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Gourlay, P. K Ballaux, E. R. Draper, and K. M Taylor Early experience with a new technique and technology designed for the study of pulsatile cardiopulmonary bypass in the rat Perfusion, May 1, 2002; 17(3): 191 - 198. [Abstract] [PDF]
|
|
|
|
|
|
T. Nakano, R. Tominaga, S. Morita, M. Masuda, I. Nagano, K.-i. Imasaka, and H. Yasui Impacts of pulsatile systemic circulation on endothelium-derived nitric oxide release in anesthetized dogs Ann. Thorac. Surg., July 1, 2001; 72(1): 156 - 162. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Undar, K. M Koenig, O H Frazier, and C. D Fraser Jr Impact of membrane oxygenators on pulsatile versus nonpulsatile perfusion in a neonatal model Perfusion, March 1, 2000; 15(2): 111 - 120. [Abstract] [PDF]
|
|
|
|
|
|
A. Undar, T. Masai, S.-Q. Yang, J. Goddard-Finegold, O.H. Frazier, and C. D. Fraser Jr Effects of perfusion mode on regional and global organ blood flow in a neonatal piglet model Ann. Thorac. Surg., October 1, 1999; 68(4): 1336 - 1342. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 K Houlind, E V Stenbog, K E Sorensen, K Emmertsen, O K Hansen, L Rybro, and V E Hjortdal Pulmonary and caval flow dynamics after total cavopulmonary connection Heart, January 1, 1999; 81(1): 67 - 72. [Abstract] [Full Text]
|
|
|
|
|
|
A. Undar, M. C Holland, R. V Howelton, C. K Benson, J. R Ybarra, O L. Miller, M. M Rossbach, T. M Runge, S. B Johnson, E. Y Sako, et al. Testing neonate-infant membrane oxygenators with the University of Texas neonatal pulsatile cardiopulmonary bypass system in vitro Perfusion, September 1, 1998; 13(5): 346 - 352. [Abstract] [PDF]
|
|
|
|
|
|
G. Chow, I. G. Roberts, A. D. Edwards, A. Lloyd-Thomas, A. Wade, M. J. Elliott, and F. J. Kirkham THE RELATION BETWEEN PUMP FLOW RATE AND PULSATILITY ON CEREBRAL HEMODYNAMICS DURING PEDIATRIC CARDIOPULMONARY BYPASS J. Thorac. Cardiovasc. Surg., October 1, 1997; 114(4): 568 - 577. [Abstract] [Full Text]
|
|
|
|
|
|
S. Y. Kim, D. E. Euler, W. R. Jacobs, A. Montoya, H. J. Sullivan, V. A. Lonchyna, and R. Pifarre Arterial Impedance in Patients During Intraaortic Balloon Counterpulsation Ann. Thorac. Surg., March 1, 1996; 61(3): 888 - 894. [Abstract] [Full Text]
|
|
|
|
 |
|
 S. A. Webber, P. Horvath, J. G. LeBlanc, Z. Slavik, R. K. Lamb, J. L. Monro, O. Reich, J. Hruda, G. G.S. Sandor, B. R. Keeton, et al. Influence of Competitive Pulmonary Blood Flow on the Bidirectional Superior Cavopulmonary Shunt : A Multi-Institutional Study Circulation, November 1, 1995; 92(9): 279 - 286. [Abstract] [Full Text]
|
|
|
|
|
|
Y. Moshkovitz, A. Lusky, and R. Mohr CORONARY ARTERY BYPASS WITHOUT CARDIOPULMONARY BYPASS: ANALYSIS OF SHORT-TERM AND MID-TERM OUTCOME IN 220 PATIENTS J. Thorac. Cardiovasc. Surg., October 1, 1995; 110(4): 979 - 987. [Abstract] [Full Text]
|
|
|
|
|
|
G. Wright The assessment of pulsatile blood flow Perfusion, May 1, 1995; 10(3): 135 - 140. [PDF]
|
|
|
|
|
|
G. Wright Hemodynamic analysis could resolve the pulsatile blood flow controversy Ann. Thorac. Surg., October 1, 1994; 58(4): 1199 - 1204. [Abstract] [PDF]
|
|
|
|
|
|
W. Rees, A. Schiessler, F. Schulz, R. Hetzer, and K. Affeld Pulsatile extracorporeal circulation: fluidmechanic considerations Perfusion, November 1, 1993; 8(6): 459 - 469. [Abstract] [PDF]
|
|
|
|
|
|
M. P. Anstadt, M. Tedder, S. S. Hegde, R. A. Perez-Tamayo, B. J. Crain, V. L. Khian Ha, S. Abdel-Aleem, W. D. White, and J. E. Lowe Pulsatile versus nonpulsatile reperfusion improves cerebral blood flow after cardiac arrest Ann. Thorac. Surg., September 1, 1993; 56(3): 453 - 461. [Abstract] [PDF]
|
|
|
|
|
|
R. A. Guyton, J. P. A. M. Schonberger, P. A. M. Everts, G. K. Jett, L. A. Gray Jr, I. Gielchinsky, D. H. Raess, G. J. Vlahakes, S. R. Woolley, D. M. Gangahar, et al. Postcardiotomy shock: Clinical evaluation of the BVS 5000 biventricular support system Ann. Thorac. Surg., August 1, 1993; 56(2): 346 - 356. [Abstract] [PDF]
|
|
|
|
|
|
S. Ohri and P. Abel Review article : The pathophysiology of nephrourological complications following cardiopulmonary bypass Perfusion, April 1, 1991; 6(2): 79 - 91. [PDF]
|
|
|
|
 |
|
 J. Hager, F. Brandstaetter, O. Dietze, I. Koller, and F. Unger The Spindle Pump--A Nonpulsatile Blood Pump for Assisted Circulation J Biomater Appl, January 1, 1990; 4(3): 225 - 330. [PDF]
|
|
|
|
|
|
G. S. Weinstein, P. S. Rao, G. Vretakis, and D. H. Tyras Serial changes in renal function in cardiac surgical patients Ann. Thorac. Surg., July 1, 1989; 48(1): 72 - 76. [Abstract] [PDF]
|
|
|
|
|
|
G. Wright The hydraulic power outputs of pulsatile and nonpulsatile cardiopulmonary bypass pumps Perfusion, October 1, 1988; 3(4): 251 - 262. [Abstract] [PDF]
|
|
|
|
|
|
K. Taylor Review article : Vasopressor release and multiple organ failure in cardiac surgery Perfusion, January 1, 1988; 3(1): 1 - 16. [PDF]
|
|
|
|
|
|
G. Wright and A. Furness What Is Pulsatile Flow? Ann. Thorac. Surg., May 1, 1985; 39(5): 401 - 402. [PDF]
|
|
|
|
|
|
P. R. Hickey, M. J. Buckley, and D. M. Philbin Pulsatile and Nonpulsatile Cardiopulmonary Bypass: Review of a Counterproductive Controversy Ann. Thorac. Surg., December 1, 1983; 36(6): 720 - 737. [Abstract] [PDF]
|
|
|
|
|
|
J. D. Sink, W. R. Chitwood Jr, R. C. Hill, and A. S. Wechsler Comparison of Nonpulsatile and Pulsatile Extracorporeal Circulation on Renal Cortical Blood Flow Ann. Thorac. Surg., January 1, 1980; 29(1): 57 - 62. [Abstract] [PDF]
|
|
|
|
|
|
G. L. Zumbro Jr., G. Shearer, M. E. Fishback, and R. F. Galloway A Prospective Evaluation of the Pulsatile Assist Device Ann. Thorac. Surg., September 1, 1979; 28(3): 269 - 273. [Abstract] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
| ANN THORAC SURG | ASIAN CARDIOVASC THORAC ANN | EUR J CARDIOTHORAC SURG |
| J THORAC CARDIOVASC SURG | ICVTS | ALL CTSNet JOURNALS |
