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Ann Thorac Surg 1978;25:99-106
© 1978 The Society of Thoracic Surgeons


Articles

Tumors of the Thymus and Thymic Region: II. Clinicopathological Studies on Hodgkin's Disease of the Thymus

N.P. Bergh, M.D., P. Gatzinsky, M.D., S. Larsson, M.D.*, P. Lundin, M.D., B. Ridell, M.D.

Departments of Thoracic Surgery and Pathology I, Sahlgren's Hospital, University of Göteborg, Gothenburg, Sweden.

Accepted for publication June 21, 1977.

* Address reprint requests to Dr. Larsson, Thoracic Surgical Clinic, Sahlgren's Hospital, 413 45 Gothenburg, Sweden

Among 82 patients with a tumor in the thymic region, 17 had a lesion that fulfilled the criteria for Hodgkin's disease of the thymus; the histopathological differentiation of this entity from thymomas is discussed. All patients received surgical treatment and postoperative radiotherapy. After a mean observation time of 10 years there was no local recurrence and no death due to the disease, though 3 deaths were caused by the treatment. New clinical manifestations occurred in 3 of the 14 long-term survivors; they were treated successfully by operation or irradiation.

A very aggressive surgical approach involving extirpation of all tumor tissue, extensive excision of the surrounding tissues and adjacent lymph nodes, and supplementary radiotherapy seems to be the treatment of choice.







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Copyright © 1978 by The Society of Thoracic Surgeons.