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Ann Thorac Surg 1977;24:433-438
© 1977 The Society of Thoracic Surgeons
Department of Surgery, Section of Thoracic Surgery, The University of Michigan Medical Center, Ann Arbor, MI.
* Address reprint requests to Dr. Kirsh, C-7175 University Hospital, Ann Arbor, MI 48109
Endocarditis involving a prosthetic aortic valve is associated with persistently positive blood cultures and aortic regurgitation. With rare exception, it is a fatal disease. An experimental technique was developed that would allow for removal of the infected aortic prosthesis with debridement and permanent closure of the aortic root. An extraanatomical outflow for the left ventricle was created using a valve-containing conduit between the apex of the left ventricle and the descending thoracic aorta (apicoaortic anastomosis).
The procedure was performed on 5 mongrel dogs through a left thoracotomy without use of cardiopulmonary bypass. Four survived the procedure and required no cardiotonic support. One died as a result of a technical problem. Intraoperative pressure determination revealed a 0 to 15 mm Hg gradient across the apicoaortic prosthesis and a left ventricular enddiastolic pressure of 0 to 4 mm Hg. Both postoperative angiocardiogram and postmortem examination confirmed patency of the aortocoronary bypass grafts and good function of the prosthesis.
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