The Annals of Thoracic Surgery, Vol 24, 284-288, Copyright © 1977 by The Society of Thoracic Surgeons
Chronic interstitial pneumonitis with fibrosis after long-term therapy with nitrofurantoin
SJ Simonian, EJ Kroeker and DP Boyd
Nitrofurantoin has been used widely as a urinary antiseptic. That it may
cause pulmonary infiltration, and even fibrosis, has not been recognized
universally. The literature contains 24 cases of interstitial pneumonitis
with fibrosis. The results of treatment are summarized, and a new case is
reported in detail.