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Claude W. Smith
Gordon F. Murray
Benson R. Wilcox
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Ann Thorac Surg 1977;24:54-58
© 1977 The Society of Thoracic Surgeons

Articles

The Role of Transbronchial Lung Biopsy in Diffuse Pulmonary Disease

Claude W. Smith, M.D., Gordon F. Murray, M.D.*, Benson R. Wilcox, M.D., Peter J.K. Starek, M.D., David J. Delany, M.D.

From the Division of Cardiothoracic Surgery, University of North Carolina School of Medicine, Chapel Hill, NC

* Address reprint requests to Dr. Murray, Division of Cardiothoracic Surgery, University of North Carolina School of Medicine, Clinical Sciences Bldg 229H, Chapel Hill, NC 27514

Forty consecutive patients underwent flexible fiberoptic transbronchial lung biopsy for diagnosis of diffuse nodular or infiltrative lung disease. Biplane fluoroscopic examination with image intensification greatly facilitated accurate placement of the biopsy forceps near the pleura. Specimens of lung parenchyma were obtained for culture and histological study in every case. A pathological diagnosis was correctly established in 34 of 40 patients. Transbronchial biopsy was helpful in the clinical management of an additional 4 patients. Biopsy results were not accurate in 2 patients. No significant morbidity was associated with the procedure. Fiberoptic transbronchial lung biopsy is a safe and useful adjunct to the diagnosis of parenchymal lung disease.




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